DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1494 and ytfR

DIOPT Version :9

Sequence 1:	NP_001259763.1	Gene:	CG1494 / 33102	FlyBaseID:	FBgn0031169	Length:	1695	Species:	Drosophila melanogaster
Sequence 2:	YP_026286.1	Gene:	ytfR / 2847725	ECOCYCID:	EG12518	Length:	500	Species:	Escherichia coli

Alignment Length:	470	Identity:	100/470 - (21%)
Similarity:	179/470 - (38%)	Gaps:	110/470 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   557 ALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAASMELGI-- 619
            ||:...:::...|:..|:|.||.|||||:|.|.|:....|||:.:....|..:..|.:.:|||
E. coli    24 ALDNVDFSLRRGEIMALLGENGAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGT 88

  Fly   620 AFGHDMLLTGFTVIDYL-------RF-ICRVKGLHNN-IEIDGQSNYFLNVLQIGGLKTKRIRTL 675
            .:....||...:|.|.|       || :.|.|.:... .|:.....:.|:|.:    ...|....
E. coli    89 VYQEVNLLPNMSVADNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVRE----PLNRFSVA 149

  Fly   676 TDRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKR-TIILVSNSPALAENI 739
            ..:   :|:||.|...::.::::|:..:.||.:...|:::|:.:.:.:. ::|.|::.......:
E. coli   150 MQQ---IVAICRAIDLSAKVLILDEPTASLDTQEVELLFDLMRQLRDRGVSLIFVTHFLDQVYQV 211

  Fly   740 ADRMAIMSNGE-LKCTGT-----KPFLKNMYGH----------GYRLTCVKG----KNY------ 778
            :||:.::.||. :.|..|     ...:|.|.|.          |..|...|.    |||
E. coli   212 SDRITVLRNGSFVGCRETCELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI 276

  Fly   779 -------KRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFEDQFPMLIDDLEENMQQ------L 830
                   :..|:.|:........:...::.:.:      |..|....||....:|::.      |
E. coli   277 APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGI------KPADSGTALIKGKPQNLRSPHQASVL 335

  Fly   831 GVVSFRIRDTSMEEIFLRFGCEDN------DQSGAFQ--SHENAQVLLEEYYSTLAEANEKGRR- 886
            | :.|...|...:.|.......:|      .|.|..:  |.:..|.:.|.:...|      |.|
E. coli   336 G-IGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQL------GIRT 393

  Fly   887 --TGWKLFFLHG---RAVIYKRWIAAHRHWIVL-----------------IFEVLAMALVAVCTF 929
              |...:.||.|   :.|:..||:.....:::|                 :.|.|....:|:...
E. coli   394 PSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCADGLALLVI 458

  Fly   930 SSIFIYGKNYELEPL 944
            ||        |||.|
E. coli   459 SS--------ELEEL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468
		CcmA	541..848	CDD:224054	74/341 (22%)
		ABC_subfamily_A	541..761	CDD:213230	53/221 (24%)
		ABC2_membrane_3	911..>1189	CDD:289468	10/51 (20%)
		ABC2_membrane	<1080..>1188	CDD:304374
		ABC_subfamily_A	1370..1577	CDD:213230
		PRK14255	1371..1586	CDD:172743
ytfR	YP_026286.1	MglA	2..500	CDD:224053	100/470 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
SwiftOrtho	0	0.000	Not matched by this tool.
	1	1.000