Protein Alignment CG1494 and Abca9

DIOPT Version :9

• Sequence 1: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Sequence 2: NP_671753.2
• Gene: Abca9 / 217262
• MGIID: 2386796
• Length: 1623
• Species: Mus musculus
• Alignment Length: 1647
• Identity: 337/1647 - (20%)
• Similarity: 649/1647 - (39%)
• Gaps: 370/1647 - (22%)

  Fly   216 YEGGFVGY---VREGFIRL--QKSVSESFL-VLTSHKSLPTIQIRRFPITGREQDPLMGNLNYGM 274
            :|.|||.:   :..|.|.:  ..||.|..: |:.|:..:|               |.:.......
Mouse   174 WEKGFVAFQAAINAGIIEMITNHSVMEELMSVIGSNMKMP---------------PFIAQGGVAT 223

  Fly   275 PFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLIN----MNIGNLIHFVSWYLKGLIYEMISSLIIA 335
            .|.|....:..:.|..:  :|...:|.||::..    |.:.....::||.|....:.::.:::::
Mouse   224 DFFIFFCVISFSSLIYY--LSVNITQERQYMTTLMAMMGLRESAFWLSWSLMYAGFILVVAVLMS 286

  Fly   336 ALLKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNAL---NAVRVLTILW---- 393
            .::|     ...|:..|.:.::.|:...|..:.:..:.:::...:...   .|:.:||:.|
Mouse   287 LIVK-----SAQVVVLTGFMVVFLLFLFYGLSLITLSFLMSVLIKKPFLTGLAIFILTVFWGSLG 346

  Fly   394 ---IMSYVPTFILSNNLEGNIHALRYVS-YALPNVVATLVIEFLIERESIVHITWE-DSGYRLNY 453
               :..::|.|:        ...|.::| :|....:|.|           :|:.:: :|...||.
Mouse   347 FTALYKHLPAFV--------EWTLCFLSPFAFTTGMAQL-----------IHLDYDVNSNVNLNS 392

  Fly   454 DGGHITVTASSWIFMLNALVYCAIGLYVDMWRGGDRSGKKMKKPNTNASVQEDP---------YH 509
            ......:.|:.::.:|:||:|..:.||.|            |...:....|..|         :.
Mouse   393 PNNSYLIMATLFMLVLDALLYLVLALYFD------------KITLSKYGHQRSPLFFLKSSYWFK 445

  Fly   510 ERGDSFTHQGQAIGVNSTKIYEVEPSHRRFK----LKIKKLCKRFATNDR--PALNLFSWNVYEN 568
            .||.|.......|..:.:....:||....|:    ::||.|.|.::....  .||....:::||.
Mouse   446 RRGASHVVLENEIDSDPSLNDSLEPVSPEFQGKEAIRIKNLKKEYSGKHGKVEALRGLGFDIYEG 510

  Fly   569 EVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAASMELGIAFGHDMLLT----- 628
            ::|.|:||:|.||:||:..|:||..|:.|:|.|.:..:      :.|:     ..|.:||
Mouse   511 QITALLGHSGAGKTTLINTLSGLSPPTTGSVTIYNQTV------SEMD-----DSDAVLTITGVC 564

  Fly   629 -------GF-TVIDYLRFICRVKGL--HNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDRDLCLV 683
                   || ||.:.||...::||:  |   |::.:....|..|::..::....:.|:......:
Mouse   565 PQSNVQFGFLTVRENLRLFAKIKGILPH---EVEQEVQQVLQDLEMENIQDILAQNLSGGQKRKL 626

  Fly   684 SICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKRTIILVSNSPALAENIADRMAIMSN 748
            ::..|.:|:..::|:|:..:.||..::..:|||:.|.::.|.|:..:.....|:.:|||...:||
Mouse   627 TLGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKERRAGRVIVFSTQFMDEADILADRKVFISN 691

  Fly   749 GELKCTGTKPFLKNMYGHGYRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFE 813
            |.|||.|:..|||..:|.||.|:....:....:.:..::..::.:..:......::.::|..:..
Mouse   692 GRLKCAGSSLFLKKKWGIGYHLSLHLNEACDPEGITSLVKKHISDARLTTQSEERLVYILPLERT 756

  Fly   814 DQFPMLIDDLEENMQQLGVVSFRIRDTSMEEIFLRF-GCEDNDQS-----GAFQSHENAQ----- 867
            ::||.|..||:....| |:..:.:..|::.|:||:. |....|:|     |..|| :.|:
Mouse   757 NKFPDLYRDLDRCSNQ-GIEDYGVSMTTLNEVFLKLEGKSMADESDVGICGRLQS-DGARDMESL 819

  Fly   868 VLLEEYYSTLAEANEKGRRTGWKLFFLHGRAVIYKRW--IAAHRHWIVLIFEVLAMALVAVCTFS 930
            |.||:..|..:..:.......|:....   ||...|:  :...|..::.:..:..::.|......
Mouse   820 VELEQVLSLDSSGSSVSGMALWRQQLC---AVAKVRFFKLKNERKSLMTVLLLFGISFVPQLLEH 881

  Fly   931 SIF-IYGKNYE--LEPLTFNLSQ--------LH---------TVDAFVELFSEEEDVKDMHAYYT 975
            .:: :|.|:|.  |.|..:.||.        .|         ::|.||....::....|:.|..|
Mouse   882 LVYKVYHKSYSWGLSPSMYFLSPGQPPQDPLTHLLVINRTGSSIDNFVHALRQQGIALDLDALGT 946

  Fly   976 -----ELLYWYDAHVATLTKNRHNAYALLTQN---QFTAHVNSRYIFGATFDQKIVTAWFNNIPL 1032
                 |.||             :.|..:|.:.   :|:...|::                   .|
Mouse   947 RNGTEEALY-------------NGAITVLGEEKALRFSVACNAK-------------------RL 979

  Fly  1033 HSAPYALNVVHNAVARHLFDEEATIDVTLAPLPFRTAINTFPPSSHTFGGCLAFGICFVL-TFIW 1096
            :..|..::::.|.:. .:|:....|..               ..|..|...:.:...|:. .|.|
Mouse   980 NCFPVLMDIISNGLL-GIFNSSERIQT---------------DRSTVFEEHMLYEYGFMSNAFFW 1028

  Fly  1097 --------PAFAIYMITERGSLLKKQQFLAGVRVCSYWTFTVLYD--LLFLLIFCACVVVMVALY 1151
                    |..|:..|::....:..|.:.:|:...:||....|.|  :.||::|  .:.:|.:::
Mouse  1029 IPVAASLTPYIAMGSISDHKKKVLSQLWTSGLYPSAYWCGQALVDIPIYFLILF--LMQIMDSVF 1091

  Fly  1152 ENPNHDVML----------YGYISVTLML--------------GGFW-----VILLAYLMASLCR 1187
            .:.....::          .||.|..:.:              .|.|     ::.:.:::|:...
Mouse  1092 SSEEFISVMESLLIQIPCSIGYASSLIFMTYVISFIFRNGRKNSGIWSFFFLIVTIFFIIATDIN 1156

  Fly  1188 NPCYGFLWLCGINSIGLVCFSQFYRTHPESMLLEPTFMAMYTVATVICKLFMIYEFKLICMDPVV 1252
            .  ||||.|       |:|           ..|.|.|       |:|..|.:..|.....:|.:.
Mouse  1157 E--YGFLEL-------LIC-----------TFLVPPF-------TLIGSLLIFSEVSYDSVDYLG 1194

  Fly  1253 NFTSVEVFKCNSIPNCCIKSNYGTFTAGIYHDLVILTLLDIILLACLFVSEYHSILGFADCRLDT 1317
            ...|..||....||       |..|            ||...:|.||     ...|.....|:|.
Mouse  1195 TSESQLVFLALLIP-------YLHF------------LLFFFILRCL-----ERYLRKKSLRVDP 1235

  Fly  1318 RTNESPDS-----NQESRAFPGILSNDTAALVDKEHT----SRLNEEE---------RSKYAAVG 1364
            ....||.|     |.|.   ||  ..|....:::..|    :.|..:|         |.:|....
Mouse  1236 VFRISPRSCPAVPNPEE---PG--EEDEDVQMERVRTTGAMATLQTDEKPVIIASCLRKEYIGRT 1295

  Fly  1365 IGIVSKYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWIHDYSVNTHR 1429
            ....||.::....|::.|.:.|.|.|.:.|.|.:||:|.:.::..:|...|||:::.......
Mouse  1296 KRCFSKMKKKIATRNISFCVKKGEVLGLLGHNGAGKSTTISMITGDTIPTAGQVFLKGSGGGA-- 1358

  Fly  1430 VQCYRMVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELSEALLRLVGLTPCWNRSVRMCT 1494
              ....:|||||::.|....|.:|.|.::|.::|.:.:........|:..:.|.......||..:
Mouse  1359 --ALGFLGYCPQENVLWPNLTVKEHLELYAAVKGLKKKDAVVTITRLVNALKLQDHLKALVRTLS 1421

  Fly  1495 TGQIRRLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTMQAMGSSFLYT----MLTG--- 1552
            .|..|:|.|..::||:|.::.:|....|:||.|::      ...||:.::|..|    :||.
Mouse  1422 EGVKRKLCFVLSILGNPPVVLLDEPSTGMDPEGQQ------QMWQAIRATFTNTERGALLTTHYM 1480

  Fly  1553 LDAERLSLRTPLLLEGQLWMIRPMDTETENYKSGYQLEVRFK--RKVNP-NVSMSRATWNLINHF 1614
            .:||.:..|..:::.|:|..|..:......:...|.||::.|  .:|.| |..:.|.       |
Mouse  1481 AEAEAVCDRVAIMVSGRLRCIGSIQHLKSKFGKDYLLEMKVKTPSQVEPLNTEIMRL-------F 1538

  Fly  1615 PMSP-NKKFSAFMEIKFP--------DAVLTIER--DDSMVFVLPLGTTTFSEIFLTLRKDAFEM 1668
            |.:. .:::|:.|..|.|        :|...:||  ::..:....|..:|..::||.|.|   |.
Mouse  1539 PQAARQERYSSLMVYKLPVEDVRPLSEAFFKLERLKENFDLEEYSLSQSTLEQVFLELSK---EQ 1600

  Fly  1669 NIEDYFITRNMLVGFQIFTYDQ 1690
            .::|:....|..|.:::...::
Mouse  1601 ELDDFGEEANSSVKWKLLPQEE 1622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	37/232 (16%)
		CcmA	541..848	CDD:224054	82/323 (25%)
		ABC_subfamily_A	541..761	CDD:213230	65/236 (28%)
		ABC2_membrane_3	911..>1189	CDD:289468	51/345 (15%)
		ABC2_membrane	<1080..>1188	CDD:304374	23/147 (16%)
		ABC_subfamily_A	1370..1577	CDD:213230	54/213 (25%)
		PRK14255	1371..1586	CDD:172743	53/221 (24%)
Abca9	NP_671753.2	rim_protein	<128..1600	CDD:130324	333/1623 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750