Protein Alignment CG1494 and abt-5

DIOPT Version :9

• Sequence 1: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Sequence 2: NP_001364572.1
• Gene: abt-5 / 173081
• WormBaseID: WBGene00000023
• Length: 1582
• Species: Caenorhabditis elegans
• Alignment Length: 1574
• Identity: 355/1574 - (22%)
• Similarity: 637/1574 - (40%)
• Gaps: 283/1574 - (17%)

  Fly   234 SVSESFLVLTSHKSLPTIQIRRFPITGREQDPLMGNLNYGMPFIIIIGFLFPAQLFVWQVVSEKQ 298
            |:.|:|            .|:.:.||..|:...  ..|:|:.|.:.:  |.|.......:|.||
 Worm   175 SIIENF------------DIKLYSITNFEESGF--GQNFGLLFAVCM--LMPVISVARALVVEK- 222

  Fly   299 SQVRQFLINMNIGNLIHFVSWYLKGLIYEMISSLIIAALLKIRWDQDHGVLTQTPWYILILVLFC 363
            |.|:.:|..:.:...:.::..:|.|:|.......:::.|.....|       ..|.|:| ..:|.
 Worm   223 SSVKPYLTTIGLPLWMFYLEHFLFGVIKNTFLITLLSTLYIFSMD-------NCPTYVL-AGIFM 279

  Fly   364 YNCAAVAFAIMVAAFFRNALNAVRVLTILWIMSYVPTFILSN--NLEGNIHALRYVSYALPNVVA 426
            |.|..|:|:|:..:........|..:.|:||     |.|::.  :||.....|.:|....||...
 Worm   280 YTCHCVSFSILCTSILPFGKRIVEGMVIIWI-----TLIIAMHLSLEFEFDWLFWVPLLNPNYSL 339

  Fly   427 TLVIE--FLIE--RESIVHITWEDSGYRLNYDGGHITVTASSWIFMLNALV-----YCAIG--LY 480
            .|.::  ||..  ..:.....:......|.....:..:..|..:.||.|.:     |..:|  ::
 Worm   340 KLFVDATFLASGPNGTPTSALFSSKKKTLQSAAVYFGIMISCTVVMLVAAIFMEKLYTFVGHAIF 404

  Fly   481 VDMWR-GGDRSGKKMKKPNTNASVQEDPYHERGDSFTHQGQAIGVNST------KIYEVEPSHRR 538
            ...|| .|...||:.|            ..||||....:...:....|      .|.::|
 Worm   405 KRFWRILGFSKGKRSK------------IEERGDGVEDRSTILQCKETVEGRGSAIADIE----- 452

  Fly   539 FKLKIKKLCKRFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISS 603
                :..|.|.: .|...|:|..|......:|::|:|||||||||...::.|:.:.:.|.|||..
 Worm   453 ----LSGLVKVY-QNGEKAVNGLSLRAIRGQVSILLGHNGCGKSTTFGMITGMHQATEGKVMIGG 512

  Fly   604 HNIQTERKAASMELGIAFGHDMLLTGFTVIDYLRFICRVKG-------------LHNNIEIDGQS 655
            .:....|..|...:|....::.:....||.::||.:..:||             |...||:..:.
 Worm   513 IDANANRAEARELIGYCPQYNPIYDELTVWEHLRLVNALKGRSGGSDFKMDAESLLKQIELTDKR 577

  Fly   656 NYFLNVLQIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEE 720
            |.....|. ||:|         |.||   :|.|.:|.|.:||:|:..:.:|...:..|.|::...
 Worm   578 NTLAKNLS-GGMK---------RKLC---VCMAMIGGSRVILLDEPTAGMDPSARIDVQNMLALV 629

  Fly   721 KSKRTIILVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTCV---------KGK 776
            |:.|||:|.::....||.:.|.:.:||:|::..:|:|.:||..||.|..||.|         ..|
 Worm   630 KADRTILLTTHYMDEAEKLGDWIFVMSHGKMAASGSKHYLKQKYGGGMLLTLVFKSVHDPMRPRK 694

  Fly   777 NYK---------------RDELFGMMNSYMPNMSI---ERDIGYKVTFVLENKFED-----QFPM 818
            :|:               :||     ...|..:||   |:.....:..:||:..|:     :|..
 Worm   695 SYETAYDVCKTVCSTALVKDE-----RGQMIEISILETEKSRLPTLLKILESVMEEDYNNPEFQA 754

  Fly   819 LIDDLEENMQQLGVVSFRIRDTSMEEIFLRFG--CED-NDQSGAFQSHENAQVLLEEYYSTLAEA 880
            |..|::|..:.|.:.:..:..:|:|::|::.|  |:| .:.:|..:..|.     :|.:|||.:.
 Worm   755 LEPDIQEKCRTLELATIGVSMSSLEQVFIKIGDECDDIMNGTGVDKKTER-----QEKFSTLVQY 814

  Fly   881 NEKGRRTGWKLFFLHGRAVIYKRWIAAHRHWIVLIFEVLAMALVAVCTFSSIFIYGKNYELEPLT 945
            ..:..:.|:....:...|::.||....:|:.:.:..::: :.|:.:..|:..|:     .|||..
 Worm   815 KIQQPKQGFSKLMMVVWALLQKRAYYLYRNPVQITLQII-LPLLTLWLFAVPFL-----RLEPKP 873

  Fly   946 FNLSQLHTVD--------AFVELFSEEED----VKDMHAYYTELLYWYDAHVATLTKNRHNAYAL 998
            ..||.:.:.|        ..::|.:|.:|    ..:..:.:..:...|:.|...|.|.....:..
 Worm   874 PKLSDIESFDPSQYPHSTVLLQLENENDDRLANYLNSFSNFEVVKVGYNDHYGYLVKKYSQVFKT 938

  Fly   999 LTQNQFTAHVNSRYIFGATFDQKIVTAWFNNIPLHSAPYALNVVHNAVARHLFDEEATIDVTLAP 1063
            |   .|...||.:   |.:...||.....|      |...:|::  |.|.:|.|...|      .
 Worm   939 L---GFIVKVNKK---GDSKFYKISQGDKN------AAILMNII--ASAMYLRDPSVT------K 983

  Fly  1064 LPFRTA-INTFPPSSHTFGGCLAF----GICF--VLTFIWPAFAIYMITERGSLLKKQQFLAGVR 1121
            ||..|: :.........:.|..:|    .|.|  ||..|:....:|:|.|:......||:|.|:.
 Worm   984 LPHVTSRVIWMNDPKIKYEGLASFFLFENIFFLLVLAGIFIQSTVYLIEEKICKFAHQQYLTGLS 1048

  Fly  1122 VCSYWTFTVLYDLL---FLLIFCACVVVMVALYENPNHD--VMLYGYISVTLMLGGFWVILLAYL 1181
            ..:||....|:|.|   |.|::....::...:.:...|:  |:.||.:        |:...|.||
 Worm  1049 TIAYWGVVFLWDFLLFTFFLLYTIGFLISFGVLQGHIHEIVVIFYGLL--------FYFAPLVYL 1105

  Fly  1182 MASLCRNPCYG-FL--WLCGINSIGLVCFSQFYRTHPESMLLEPTFMAMYTVATVICKLFMIYEF 1243
            .::|...|..| ||  ..|.|..:.....|:.:...|                  |.|.....|:
 Worm  1106 TSALINTPTRGNFLLYMFCCIPWLAYSIVSELHNFPP------------------IQKYSDEIEY 1152

  Fly  1244 KLICMDPVVNFTS--VEVFKCNSIPNCCIKSNYGTFT-----AGIYHDLVILTLLDI---ILLAC 1298
            .....:|.:.|.:  :::...| .|...:..::...|     .||:.:|:.|....|   |||.|
 Worm  1153 GFRIFNPSIGFLAGLMKIAALN-YPKSGLDKHFEHLTNLWTYEGIFFELMFLFFGGIFLTILLGC 1216

  Fly  1299 LFVSEYHSILGFADCRLDTRTNESPDSNQESRAFPGILSNDTAALVDKEHTSRLNEEERSKYAAV 1363
            ..:..:...     |...||....|   :|.:.:.||.|....    ||....:.|.::::...|
 Worm  1217 ATLKPFRRA-----CFRGTRRRSQP---RERKRYKGIESCKAV----KEEEQLVQEVDKNETVLV 1269

  Fly  1364 GIGIVSKYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWI--HDYSVN 1426
            ..|:|..:.:.|.:.||..::...||..:.|||.:||||...::...|....|...|  ||.:..
 Worm  1270 IDGLVKDFGKFRAVNDLSISVGHEECFGMLGANGAGKTTTFDIITGLTMPTGGSATIDGHDITET 1334

  Fly  1427 THRVQCYRMVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELSEALLRLVGLTPCWNRSVR 1491
            .|       :|||||.|::..:.:.|:.|.|.|.|||:.:  .:|:.|.:|..||::....:.|:
 Worm  1335 IH-------IGYCPQFDAMLQQISCRQTLRIMAKLQGYPN--VKEVVELVLDCVGMSDFGYKLVK 1390

  Fly  1492 MCTTGQIRRLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTMQAMGS-SFLYTMLTGLDA 1555
            .|:.||.|::....|::.....|.:|...||:||..:|.|..:...|:.... |.:.|..:..:.
 Worm  1391 NCSGGQKRKISVGIALMSRATCIILDEPTAGIDPRARREIWDIIHEMREQAKCSIVLTSHSMEEC 1455

  Fly  1556 ERLSLRTPLLLEGQLWMIRPMDTETENYKSGYQLEVRFKRKVNPNVSMSRATWNLINHFPMSPNK 1620
            |.|..|..:|.:|::..:....:....|.:.|.:.:                  ::|  .:...:
 Worm  1456 EALCTRIGILRKGEMIALGTSQSLKSQYGNTYMMTL------------------ILN--SLEDLE 1500

  Fly  1621 KFSAFMEIKFPDAVLTIERDD---SMVFVLPLG-TTTFSEIFLTLRKDAFEMNIEDYFITRNML- 1680
            .....:..:.|||||......   |:|:.||.. :..:||.:..:...|.:.|.:||.:|:..|
 Worm  1501 SVCVIVSEEMPDAVLKTPESSLTTSIVWELPKSKSDKWSEKYNQVEVLAKKANAKDYMLTQASLE 1565

  Fly  1681 -VGFQIFTYDQHQD 1693
             ...::.|.::.::
 Worm  1566 DTFIRLITTEEEEE 1579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	47/229 (21%)
		CcmA	541..848	CDD:224054	92/351 (26%)
		ABC_subfamily_A	541..761	CDD:213230	65/232 (28%)
		ABC2_membrane_3	911..>1189	CDD:289468	64/301 (21%)
		ABC2_membrane	<1080..>1188	CDD:304374	30/118 (25%)
		ABC_subfamily_A	1370..1577	CDD:213230	58/209 (28%)
		PRK14255	1371..1586	CDD:172743	59/217 (27%)
abt-5	NP_001364572.1	rim_protein	<419..1569	CDD:130324	295/1288 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880