DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1494 and AgaP_AGAP002060

DIOPT Version :9

Sequence 1:	NP_001259763.1	Gene:	CG1494 / 33102	FlyBaseID:	FBgn0031169	Length:	1695	Species:	Drosophila melanogaster
Sequence 2:	XP_320987.5	Gene:	AgaP_AGAP002060 / 1281053	VectorBaseID:	AGAP002060	Length:	736	Species:	Anopheles gambiae

Alignment Length:	216	Identity:	60/216 - (27%)
Similarity:	100/216 - (46%)	Gaps:	29/216 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1365 IGIVSKYR---------RNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWI 1420
            :.::|.|:         :..||..|:.::.:.....:.||:..||||||..:|....:|.|::.:
Mosquito     4 VEVISGYKYYGKANDPNKKIVLNHLNMSVTRGSIYGLLGASGCGKTTLLSCIVGRKFLNDGEINV 68

  Fly  1421 HDYSVNT--HRVQCYRMVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELSEALLRLVGLT 1483
            ...:..|  ..|...| :||.||..:|..|||.:|.:|....:.|......||..:.|..|:.|
Mosquito    69 LGGTPGTAGSGVPGPR-IGYMPQDIALVEEFTIKETIYYFGRIYGMSKEKIRERYKLLKHLLEL- 131

  Fly  1484 PCWNRSVRMCTTGQIRRLYFAYAVLGSPDLICVDGVPAGLDP---------------TGKRIILM 1533
            |..:|.|..|:.||.||:.||.|::..|:|:.:|....||||               |.|..:::
Mosquito   132 PGDDRYVGNCSGGQQRRVSFAAAMVHEPELLILDEPTVGLDPLLREKIWQYLVETTSTSKMAVII 196

  Fly  1534 MTSTM-QAMGSSFLYTMLTGL 1553
            .|..: :|..:.|:..|..|:
Mosquito   197 TTHYIEEAKQAGFIGLMRNGI 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468
		CcmA	541..848	CDD:224054
		ABC_subfamily_A	541..761	CDD:213230
		ABC2_membrane_3	911..>1189	CDD:289468
		ABC2_membrane	<1080..>1188	CDD:304374
		ABC_subfamily_A	1370..1577	CDD:213230	59/211 (28%)
		PRK14255	1371..1586	CDD:172743	59/210 (28%)
AgaP_AGAP002060	XP_320987.5	EcfA2	1..230	CDD:224047	60/216 (28%)
		P-loop_NTPase	11..224	CDD:304359	58/209 (28%)
		ABC2_membrane_3	349..712	CDD:289468
		ABC2_membrane	530..689	CDD:279410
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810