Protein Alignment CG1494 and AgaP_AGAP010582

DIOPT Version :9

• Sequence 1: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Sequence 2: XP_314549.4
• Gene: AgaP_AGAP010582 / 1275311
• VectorBaseID: AGAP010582
• Length: 1610
• Species: Anopheles gambiae
• Alignment Length: 1359
• Identity: 292/1359 - (21%)
• Similarity: 540/1359 - (39%)
• Gaps: 289/1359 - (21%)

  Fly   466 IFMLNALVYCAIGLYVDMWRGGDRSGKKMKKPNTNASV-----QEDPYHERGDSFTHQGQAIGVN 525
            :.:|:|::|..||.....::..:.:...:|:...:.|:     ..|..:|:|      |:.:
Mosquito   407 MILLDAVIYFTIGYLYQCFKKDETTFHTVKRIKLDKSIGAELRNVDVAYEKG------GKKV--- 462

  Fly   526 STKIYEVEPSHRRFKLKIKKLCKRFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAG 590
               :.:|..:.||                             :|||.|:|.||.||||::|:|.|
Mosquito   463 ---LSDVSITFRR-----------------------------DEVTCLLGRNGAGKSTIIKLLTG 495

  Fly   591 LVEPSRGTV-------MISSHNIQTERKAASMELGIAFGHDMLLTGFTVIDYLRFICRVKGLHNN 648
            .|.|..|.|       .||......|:      :|:...:|:|:...|..::|:...|:|....
Mosquito   496 QVRPIEGDVHLPLDYDFISGIRNNAEK------IGLCPQNDVLIPNLTAKEHLQLYARIKLTRG- 553

  Fly   649 IEIDGQSNYFLNVLQIGGLKTKRIRTLT---DRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQ 710
              .|.:.:..|..|::|..:..|...|:   .|.||   |..||:|:..::::|:..|.:|.:.:
Mosquito   554 --FDTEVSRTLENLKMGPYQHYRASDLSGGFKRRLC---IAIAFLGSPNLVILDEPCSSVDTKAR 613

  Fly   711 SLVWNLINEEKSKRTIILVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTC-VK 774
            ..:|.||...:..|.:||.::....||.::|::.::.||:.....::..||..:.:...|:. :|
Mosquito   614 KYIWELIQTLRKDRAVILATHHLDEAECLSDKIVMLENGKAILEQSQEELKKRFTNTIYLSIFLK 678

  Fly   775 GK-NYKRDELFGMMNSYMPNMSIERDIGY-------KVTFVLENKFEDQFPMLIDDLEENMQQL- 830
            .: :..|..:...::..:....   |:.|       ::.|.:.:...|.  .:|:.|.|:|.||
Mosquito   679 HQTDVDRTVMIAQLSKLLDGTV---DLRYDMSATLNQLDFKITSSTNDS--QVIEPLLEHMAQLK 738

  Fly   831 ---GVVSFRIRDTSMEEIFLRFGCEDNDQSGAFQSHENAQVLLEEYYSTLAEANEKGRRTGWKLF 892
               .:.||.||:.::..||......|...         |..:|:....|.|.....|
Mosquito   739 SQKQIDSFEIRNENLLNIFSTVNASDPTP---------ADPMLQNGNGTSATHIPNG-------- 786

  Fly   893 FLHG----------RAVIYKRWIAAHRHW----------IVL--IFEVLAMALVAV--------- 926
             .||          .::::..:....||:          :||  |||::||..:.:
Mosquito   787 -FHGPKTNDSKLSTMSIMWTLFCKRMRHFMRNYRLLVCLLVLPTIFEIIAMGFMTIRPPGEHDLM 850

  Fly   927 CTFSSIFIYGKNYELEPLTFNLSQLHTVDAFVELFSEEEDVKDMHAYYTELLYWYDAHVATLTKN 991
            ..||:. :|.::.|                |....::.::.:|  |..:::|........::..:
Mosquito   851 VNFSTA-LYPRSAE----------------FYTNATDGDEYRD--AIVSDVLAHCTDEYCSIFNS 896

  Fly   992 RHNAY--ALLTQNQFTAHVNSRYIFGATFDQKIVTAWFNNIPLHSAPYALNVVHNAVAR-HLFDE 1053
            .:.||  .|.|.:.:|    .|...|.|.:::....|:||...||.|..||::..||.| .|.|.
Mosquito   897 SYEAYRWVLSTTDDYT----ERRYGGITINKEKNIVWYNNKGYHSMPTWLNMLDTAVLRAELNDS 957

  Fly  1054 EATIDVTLAPLPF---RTAINTFPPSSHTFGGCLAFGICFVLTFIWPAFAIYMITERGSLLKKQQ 1115
            ..||.....||..   ..::::........|..|...:.|.|  :....::|::.||....|.||
Mosquito   958 SYTIRTINHPLKIEEDELSVSSMLQQIADAGISLIILLAFSL--VVAGASVYIVNERIRGEKLQQ 1020

  Fly  1116 FLAGVRVCSYWTFTVLYDLLFLLIFCACVVVMVALYENPNHDV--MLYGYISVTLMLGGFWVILL 1178
            .||||.|.:||:.|.::|.:..||..|..|::..::..|.:..  .|.| |.:.|:..||..|..
Mosquito  1021 RLAGVNVFTYWSVTYIWDAMIFLIALALAVIVFKVFAIPAYVAREQLEG-ICLLLVFYGFATIPA 1084

  Fly  1179 AYLMASLCRNPCYGFLWLCGINSIG-------LVCFSQFYRTHPESML---LEPTFMAM--YTVA 1231
            .:|...|..:..:..:.:..:|.|.       ::.|.....|.....:   |...|:.:  :.::
Mosquito  1085 VHLFEKLFTDASFANMSIFCLNVITALGTLTIIILFDILGDTDESERIRNALNRAFLVLPQHALS 1149

  Fly  1232 TVICKLFMIYEFKLICMDPVVNFTSVEVFKCNSIPNCCIKSN-YGTFTAGIYHDLVILTLLDIIL 1295
            ..:.:|..             |:.:.|:||...|.:  .||. |.|.   ::..|:.|.::..|.
Mosquito  1150 DGLIELSK-------------NYITAEIFKRYYIDS--YKSPVYSTL---LHPHLIALAVMGFIF 1196

  Fly  1296 LACLFVSE-------YHSILGFADCRL-DTRTNESPD---------SNQESRAFPGILSNDTAAL 1343
            :......|       |:.|:|.:..:: |....::||         ..::|.....|||.|..
Mosquito  1197 MLLNIAIEYKVVQRIYNRIVGTSQPKVHDINGMDTPDYSTVISRVEGKKKSITADQILSVDNL-- 1259

  Fly  1344 VDKEHTSRLNEEERSKYAAVGIGIVSKYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVV 1408
                         |.:|...| |.....:...|::|:.|.|...||..:.|.|.:||:|:..::.
Mosquito  1260 -------------RKRYRGCG-GGGGGAKGLEVVKDVSFKLRYGECFGLLGTNGAGKSTIFAILS 1310

  Fly  1409 NETKMNAGQLWIHDYSVNTHRVQCYRMVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELS 1473
            .|...:.|....:    :||.      ..||||.:.|....|..|::..:..|: :...|.:.:.
Mosquito  1311 GELLPSGGSFTFY----STHG------PSYCPQNNFLDPLLTVEEVIVFYGKLR-NIESIDKLIM 1364

  Fly  1474 EALLRLVGLTPCWNRSVRMCTTGQIRRLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTM 1538
            |. |:...|.......|:..:.|..|:|..|.:..|..::|.:|...:.|||..:.|:......:
Mosquito  1365 ET-LKEYHLEAYRKVLVKNLSGGNRRKLCVAVSCFGQSEIILMDEPTSDLDPVTRSIVYSTIERL 1428

  Fly  1539 QAMGSSFLYTMLTGLDAERLSLRTPLLLEGQLWMIRPMDTETENYKSGYQL--------EVRFKR 1595
            .|...|.|.|..:..:.:|:..|..:|.:|:|..:...|...|.:...||:        ||.|.|
Mosquito  1429 NAQNRSILLTSHSISEIDRICQRIAILKDGELLTVDTPDRLKERFGHSYQITLYLEGLREVDFLR 1493

  Fly  1596 KVNPNVSMSRATWNLINHFPMSPNKKFSAFMEIKFPD--------------AVLTIERDDSMVFV 1646
            .:....:::|   ::|.|      |....|:...:|:              ..:||..||:...|
Mosquito  1494 VIKREFNVTR---DIILH------KNSVQFVCQIYPEGGSQREENGKPHKNGHVTIMLDDTGSLV 1549

  Fly  1647 LPLGTT-----TFSEIFLTLRKDAFEMNIEDYFITRNMLVGFQIF-----TYDQHQDNP 1695
            :..||:     |.||:||.|::.| :.|...|.|:|..:  .|:|     .:::...||
Mosquito  1550 VAPGTSTSATGTASELFLKLQRFA-QANKLRYTISRCQM--DQVFENVLQNHEEDHANP 1605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	5/13 (38%)
		CcmA	541..848	CDD:224054	76/329 (23%)
		ABC_subfamily_A	541..761	CDD:213230	55/229 (24%)
		ABC2_membrane_3	911..>1189	CDD:289468	73/306 (24%)
		ABC2_membrane	<1080..>1188	CDD:304374	33/109 (30%)
		ABC_subfamily_A	1370..1577	CDD:213230	48/206 (23%)
		PRK14255	1371..1586	CDD:172743	50/214 (23%)
AgaP_AGAP010582	XP_314549.4	CcmA	447..728	CDD:224054	71/338 (21%)
		ABC_subfamily_A	447..664	CDD:213230	62/269 (23%)
		ABC2_membrane_3	819..1201	CDD:289468	92/425 (22%)
		NatA	1253..1498	CDD:226927	64/272 (24%)
		ABC_subfamily_A	1254..1470	CDD:213230	56/243 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920