Protein Alignment CG15445 and nub1

DIOPT Version :10

• Sequence 1: NP_608436.4
• Gene: CG15445 / 33094
• FlyBaseID: FBgn0031161
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_001107052.1
• Gene: nub1 / 557021
• ZFINID: ZDB-GENE-080212-11
• Length: 583
• Species: Danio rerio
• Alignment Length: 628
• Identity: 175/628 - (27%)
• Similarity: 300/628 - (47%)
• Gaps: 78/628 - (12%)

  Fly     3 QNDNLLIQIRALLQSDGEKLWEEPYYSEDLGSIEGALENLAQKYSGMLGIDIGRCKFFLTELQEN 67
            :..:|..::.|||:.|..:||.|||.|....:....::.||:||:.::...:......|..::.:
Zfish     2 EEQHLQARLIALLRQDKIQLWLEPYRSLRDPADRLKIQELAEKYASVIQFPVEEVTSALESIRTD 66

  Fly    68 ALRTLAARREFSTTGIATLKVRRVGEHSGAT---MVEVKCSLDIVGSELQACIAKKLEVPNAAHV 129
            ..:.....:||..|.:||| |..:.:..|.|   .|:.|..|||...||:..|:::.   ...:.
Zfish    67 TSQKDEGNKEFKQTAVATL-VLHLPKEEGETKIKKVKFKTKLDITTQELKTQISQEF---GFTYF 127

  Fly   130 KCIAAGKVVSANATLADQQLKNNQQLIVI-VGDGDNSGEALYERINRIKADVE--------AVVS 185
            ..|..||::||...|.:|::|||.:::|: ....|...|...|.....:.|.|        .::|
Zfish   128 DLILCGKILSAERRLDEQKVKNNSKIMVMKTAPLDEKAEMKKEEEKTRRQDEELQKTHRGFQILS 192

  Fly   186 SKNN--------LIEMEDQNGSQVYLPPSEHKALLMGLGFCEKARAAMNRKHFEEALLLLLEADE 242
            .::.        .:|:.||.|:.:.:|..|.|||::.:||.|:.||.|.::....||..||.|:|
Zfish   193 ERDGSEDPSTTPFLEIADQKGNPLQIPDEERKALILAMGFHERGRALMKKRDHSAALSYLLRANE 257

  Fly   243 HFSTCGSKFLESVDNYALLNLDIVWCYFCLKNVTQLPDAEHRLARCSRNFGISYGDNLERLYSLK 307
            .|..|.|..|.:|||||:|.||:||||..|:.:..|.||:.||....|.|...||:...||..:|
Zfish   258 QFKKCNSAILHTVDNYAVLQLDVVWCYQALEQMECLDDAQERLEEAERCFQKCYGEKQSRLQQIK 322

  Fly   308 GKDCPERALIMRLKLLQGVIFFHQNLRNQAFECFEAAKTLLNELKINNDQLALLVDMGFEPSEAR 372
            |....|..|.:||.|||.|:.|.:...|||.:.....:.|.::|.::..:|..|.|.||...|||
Zfish   323 GHTGGEEVLFLRLHLLQTVLMFVKGNENQALDKLRDVEHLYSQLNLDPQKLQQLQDKGFSEQEAR 387

  Fly   373 MALRSCKGGTAVEQAVQFIHERRQQLKNARMKYKASERAMERRLKRSNSKDCTWVNPRSVCSLAD 437
            :.||:|:|.  |.:|...|.:|:::.:..::|.:...|   |||:..|             :|.:
Zfish   388 LGLRACRGD--VSEAENLISQRKKEKQVLKLKEQDKRR---RRLQDIN-------------TLVE 434

  Fly   438 MGFESGLATIALQRSNNDILQAVELLQTESDELTGASPWFPVTVDTTKLAQLLQLGFNENDSRVA 502
            :|||...|..||.::..|:.:|..:|...:|           ......|.|||.:||.::.:..|
Zfish   435 LGFERRDAQRALHQARGDVDKAYGMLLDAAD-----------AQHQVNLNQLLSMGFQKDMADSA 488

  Fly   503 LQNASNNMEEAIESLMCAIESEEELKAILKHVGRLAENGGQ-NLDGPSTSNASGQTQVALPAPII 566
            |:...:::::|.:.|   :|::..:.|.|:.....:.:..: :....||..:|.|.:..|...::
Zfish   489 LRMMRDDVQQATQLL---LENQAVIPADLQSPSPPSSSSEEPSTSSESTGGSSRQDEDLLVNELL 550

  Fly   567 EAVINHARVEIETYKAYERFNSDLKLSDLEYLDLPLIQEEKIL 609
            |.:..|                     :.:||||.|.:|:|::
Zfish   551 EDIPKH---------------------EEDYLDLTLDEEKKLI 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15445	NP_608436.4	Ubl_NUB1	82..159	CDD:340582	25/80 (31%)
		UBA1_NUB1_like	354..391	CDD:270477	14/36 (39%)
		UBA_like_SF	429..463	CDD:473871	9/33 (27%)
		UBA_like_SF	484..519	CDD:473871	10/34 (29%)
nub1	NP_001107052.1	Ubiquitin_5	73..157	CDD:436228	28/87 (32%)
		UBA1_NUB1_like	369..404	CDD:270477	14/36 (39%)
		UBA2_NUB1	427..461	CDD:270478	10/46 (22%)
		UBA_like_SF	470..505	CDD:473871	10/37 (27%)