Protein Alignment CG15445 and nub1

DIOPT Version :9

• Sequence 1: NP_001259756.1
• Gene: CG15445 / 33094
• FlyBaseID: FBgn0031161
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: XP_005170703.1
• Gene: nub1 / 557021
• ZFINID: ZDB-GENE-080212-11
• Length: 584
• Species: Danio rerio
• Alignment Length: 639
• Identity: 178/639 - (27%)
• Similarity: 313/639 - (48%)
• Gaps: 76/639 - (11%)

  Fly     1 MSQNDNLLIQIRALLQSDGEKLWEEPYYSEDLGSIEGALENLAQKYSGMLGIDIGRCKFFLTELQ 65
            |.:..:|..::.|||:.|..:||.|||.|....:....::.||:||:.::...:......|..::
Zfish     1 MMEEQHLQARLIALLRQDKIQLWLEPYRSLRDPADRLKIQELAEKYASVIQFPVEEVTSALESIR 65

  Fly    66 ENALRTLAARREFSTTGIATLKVRRVGEHSGAT---MVEVKCSLDIVGSELQACIAKKLEVPNAA 127
            .:..|.....:||..|.:||| |..:....|.|   .||:|..|||...||:..|:::.   ...
Zfish    66 TDTSRKDEGNKEFKETAVATL-VLHLPREEGETKIKKVELKTKLDITTQELKKQISQEF---GFT 126

  Fly   128 HVKCIAAGKVVSANATLADQQLKNNQQLIVIVGDGDNSGEALYE-RINRIKADVE--------AV 183
            |...| .|||:|....|.:|::|||.:::|:.|...::...:|: ...:.|.|.|        .:
Zfish   127 HFNLI-CGKVLSPERRLDEQKVKNNSKIMVVKGAPPDAKAEMYKNEEEKRKQDEEIKKTQKGFQI 190

  Fly   184 VSSKNN--------LIEMEDQNGSQVYLPPSEHKALLMGLGFCEKARAAMNRKHFEEALLLLLEA 240
            :|.::.        .:|:.||.|:.:.:|..|.|||::.:||.||.||.|.::....||..|:.|
Zfish   191 LSERDGSEDPSTTPFLEIADQKGNPLQIPDEERKALILAMGFHEKGRALMKKRDHSAALPYLVLA 255

  Fly   241 DEHFSTCGSKFLESVDNYALLNLDIVWCYFCLKNVTQLPDAEHRLARCSRNFGISYGDNLERLYS 305
            ||.|..|.|..|.:|||||:|.||:||||..|..:..|.:|..||.:..:.|...||:...||..
Zfish   256 DEQFKKCNSAILHTVDNYAVLQLDVVWCYQALGQLECLDNARQRLEKAEQCFQKCYGEKQSRLQQ 320

  Fly   306 LKGKDCPERALIMRLKLLQGVIFFHQNLRNQAFECFEAAKTLLNELKINNDQLALLVDMGFEPSE 370
            :||....|..|.:||::||.::.:.:..:|||....:..:.|..||.::..:|..|.::||...|
Zfish   321 IKGHTGGEEVLFLRLRILQTLLTYIEGHKNQALGKLKDVEHLYGELSLDPQKLQQLKELGFSEQE 385

  Fly   371 ARMALRSCKGGTAVEQAVQFIHERRQQLKNARMKYKASERAMERRLKRSNSKDCTWVNPRSVCSL 435
            ||:.||:|:|.  |.:|...|.:|:::.:..::|.:...|   |||:..|             :|
Zfish   386 ARLGLRACRGD--VSEAALLITQRKKEKQVLKLKEQDKRR---RRLQDIN-------------TL 432

  Fly   436 ADMGFESGLATIALQRSNNDILQAVELLQTESDELTGASPWFPVTVDTTKLAQLLQLGFNENDSR 500
            .::|||...|..||.::..|:.:|..:|      |.||..  ..:....||.:||.:||.|:.:.
Zfish   433 VELGFERRDAQRALHQARGDVDKAYGIL------LDGADA--QKSDRDKKLNELLSMGFQEDMAD 489

  Fly   501 VALQNASNNMEEAIESLMCAIESEEELKAILKHVGRLAENGGQ-NLDGPSTSNASGQTQVALPAP 564
            .||:...:::::|.:.|   :|::..:.|.|:.....:.:..: :....||..:|.|.:..|...
Zfish   490 SALRMTGDDVQQATQLL---LENQAVIPADLQSPSPPSSSSEEPSTSSESTGGSSRQDEDLLVNE 551

  Fly   565 IIEAVINHARVEIETYKAYERFNSDLKLSDLEYLDLPLIQEEKILTEYFNMLQQ 618
            ::|.:..|                     :.:||||.|.:|::::.:...:|::
Zfish   552 LLEDIPKH---------------------EEDYLDLTLEEEKELMDKIRTILEK 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15445	NP_001259756.1	UBA1_NUB1_like	354..391	CDD:270477	13/36 (36%)
		UBA_like_SF	429..463	CDD:304366	9/33 (27%)
		UBA_like_SF	484..519	CDD:304366	11/34 (32%)
nub1	XP_005170703.1	UBL	100..157	CDD:176364	21/60 (35%)
		UBA1_NUB1_like	369..404	CDD:270477	13/36 (36%)
		UBA2_NUB1	427..461	CDD:270478	11/52 (21%)
		UBA_like_SF	474..508	CDD:304366	11/36 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592401
Domainoid	1	1.000	128	1.000	Domainoid score	I5265
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41108
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3480
OMA	1	1.010	-	-		QHG48673
OrthoDB	1	1.010	-	-		D1339766at2759
OrthoFinder	1	1.000	-	-		FOG0005370
OrthoInspector	1	1.000	-	-		otm25023
orthoMCL	1	0.900	-	-		OOG6_106196
Panther	1	1.100	-	-	O	PTHR12948
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5142
SonicParanoid	1	1.000	-	-		X4302
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940