Protein Alignment CG15445 and Nub1

DIOPT Version :10

• Sequence 1: NP_608436.4
• Gene: CG15445 / 33094
• FlyBaseID: FBgn0031161
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_001292193.1
• Gene: Nub1 / 53312
• MGIID: 1889001
• Length: 638
• Species: Mus musculus
• Alignment Length: 660
• Identity: 181/660 - (27%)
• Similarity: 308/660 - (46%)
• Gaps: 98/660 - (14%)

  Fly     1 MSQNDNLLIQIRALLQSDGEKLWEEPYYSEDLGSIEGALENLAQKYSGMLGIDIGRCKFFLTELQ 65
            |:|...|..::...|:.|..:||:.||..|: ..:..|:::||:|||..|.......:..:.|::
Mouse    25 MAQKKYLQAKLTQFLREDRIQLWKPPYTKEN-KEVGLAVKDLAKKYSERLECCENEVENIIEEIR 88

  Fly    66 ENALRTLAARREFSTTGIATLKV---RRVGEHSGATMVEVKCSLDIVGSELQACIAKKLEVPNAA 127
            ..|:........:.||||||::|   .|:.:|...:::|.:  |.:.|.:|:..||:.... ...
Mouse    89 RKAIERGTGNEHYRTTGIATIEVFLPPRLRKHDKKSLLETR--LHVTGRDLRCQIAETFGF-QEN 150

  Fly   128 HVKCIAAGKVVSANATLADQQLKNNQQLIV---------------IVGDGDNSGEALYERINRIK 177
            ::|.:...|.:....:|.:|.:.:|.:.:|               :..:..|..|....||.|.|
Mouse   151 YIKIVINKKQLQLGKSLEEQGVTHNVKAMVLELKQSEEDVRKNLQLEEEEQNEAELKERRIQRTK 215

  Fly   178 ADVEAVVSSKNNLIEME--------DQNGSQVYLPPSEHKALLMGLGFCEKARAAMNRKHFEEAL 234
            ..:|.:......:::.|        :|.|..:.:||:|.|||::.:|:.||.||.:.||.:..||
Mouse   216 RGLEILAERAEMVVDPETMPYLDIANQTGRSLRIPPAERKALMLAMGYHEKGRAFLKRKEYGIAL 280

  Fly   235 LLLLEADEHFSTCGSKFLESVDNYALLNLDIVWCYFCLKNVTQLPDAEHRLARCSRNFGISYGDN 299
            ..||:||.:|..| .:.|::|||||:|.||||||||.|:.:..|.|||.:|....:.|...||:|
Mouse   281 PCLLDADRYFCEC-KELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGEN 344

  Fly   300 LERLYSLKGKDCPERALIMRLKLLQGVIFFHQNLRNQAFECFEAAKTLLNELKINNDQLALLVDM 364
            .:||..:||....|:.|.:||.||||:..:|.....:|.|....|:.|..||.|:..::..|:.:
Mouse   345 HQRLVHIKGNCGKEKVLFLRLYLLQGIQNYHSGNGEEAREYLNKARQLFKELYIDPSKVHNLLQL 409

  Fly   365 GFEPSEARMALRSCKGGTAVEQAVQFIHERRQQLKNARMKYKASERAMERRLKRSNSKDCTWVNP 429
            ||...|||:.||:|.|.  |:.|...|..||::|...|.:.|...|   |||:..|
Mouse   410 GFTAQEARLGLRACDGN--VDHAATHISNRREELAQIRKEEKEKRR---RRLENVN--------- 460

  Fly   430 RSVCSLADMGFESGLATIALQRSNNDILQAVELLQTESDELTGASPWFPVTVD-----------T 483
                :|..||:.:..|..||.::..::..|:::|      |:....|:....|           .
Mouse   461 ----TLRGMGYSTQAAKQALHQARGNLDDALKVL------LSNPHMWWLQDADPENNSRQASPSQ 515

  Fly   484 TKLAQLLQLGFNENDSRVALQNASNNMEEAIESLMCAIESEEELKAILKHVGRLAE----NGGQN 544
            ..:.||:.:||:...:..||:....|::.|.::|             ..|.|.|..    :|..:
Mouse   516 ESINQLVYMGFDTVVAEAALRVFGGNVQLAAQTL-------------AHHGGSLPPDLQFSGEDS 567

  Fly   545 LDGPST--SNASGQTQVALPAPIIEAVINHARVEIETYKAYERFNSDLKLSDLEYLDLPLIQEEK 607
            ...|||  |:::|.:..:...            ::|| :|......|:...:.:|||..|..||.
Mouse   568 SPTPSTSPSDSAGTSSASTDE------------DMET-EAVNEILEDIPEHEEDYLDSTLEDEEV 619

  Fly   608 ILTEYFNMLQ 617
            |:.||.:.::
Mouse   620 IIAEYLSYVE 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15445	NP_608436.4	Ubl_NUB1	82..159	CDD:340582	19/94 (20%)
		UBA1_NUB1_like	354..391	CDD:270477	12/36 (33%)
		UBA_like_SF	429..463	CDD:473871	7/33 (21%)
		UBA_like_SF	484..519	CDD:473871	9/34 (26%)
Nub1	NP_001292193.1	Ubiquitin_5	94..188	CDD:436228	21/96 (22%)
		UBA1_NUB1_like	399..434	CDD:270477	12/36 (33%)
		UBA_like_SF	457..491	CDD:473871	9/52 (17%)
		UBA3_NUB1	516..551	CDD:270479	9/47 (19%)