Protein Alignment CG15445 and NUB1

DIOPT Version :9

• Sequence 1: NP_001259756.1
• Gene: CG15445 / 33094
• FlyBaseID: FBgn0031161
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: XP_016867793.1
• Gene: NUB1 / 51667
• HGNCID: 17623
• Length: 638
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 180/667 - (26%)
• Similarity: 315/667 - (47%)
• Gaps: 112/667 - (16%)

  Fly     1 MSQNDNLLIQIRALLQSDGEKLWEEPYYSEDLGSIEGALENLAQKYSGMLGIDIGRCKFFLTELQ 65
            |:|...|..::...|:.|..:||:.||..|: ..:..||::||::||..|.......:..:.|::
Human    25 MAQKKYLQAKLTQFLREDRIQLWKPPYTDEN-KKVGLALKDLAKQYSDRLECCENEVEKVIEEIR 88

  Fly    66 ENALRTLAARREFSTTGIATLKV---RRVGEHSGATMVEVKCSLDIVGSELQACIAKKLEVPNAA 127
            ..|:........:.||||||::|   .|: :.....::|.:  |.|.|.||::.||:...: ...
Human    89 CKAIERGTGNDNYRTTGIATIEVFLPPRL-KKDRKNLLETR--LHITGRELRSKIAETFGL-QEN 149

  Fly   128 HVKCIAAGKVVSANATLADQQLKNNQQLIV---------------IVGDGDNSGEALYERINRIK 177
            ::|.:...|.:....||.:|.:.:|.:.:|               :..:..|..:...::|.|.|
Human   150 YIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTK 214

  Fly   178 ADVEAVVSSKNNLIEME--------DQNGSQVYLPPSEHKALLMGLGFCEKARAAMNRKHFEEAL 234
            ..:|.:......:::.|        :|.|..:.:||||.|||::.:|:.||.||.:.||.:..||
Human   215 RGLEILAKRAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIAL 279

  Fly   235 LLLLEADEHFSTCGSKFLESVDNYALLNLDIVWCYFCLKNVTQLPDAEHRLARCSRNFGISYGDN 299
            ..||:||::|..|..:.|::|||||:|.||||||||.|:.:..|.|||.:|....:.|...||:|
Human   280 PCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGEN 344

  Fly   300 LERLYSLKGKDCPERALIMRLKLLQGVIFFHQNLRNQAFECFEAAKTLLNELKINNDQLALLVDM 364
            .:||..:||....|:.|.:||.||||:..:|.....:|:|....|:.|..||.|:..::..|:.:
Human   345 HQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQL 409

  Fly   365 GFEPSEARMALRSCKGGTAVEQAVQFIHERRQQLKNARMKYKASERAMERRLKRSNSKDCTWVNP 429
            ||...|||:.||:|.|.  |:.|...|..||::|...|.:.|..:|   |||:
Human   410 GFTAQEARLGLRACDGN--VDHAATHITNRREELAQIRKEEKEKKR---RRLE------------ 457

  Fly   430 RSVCSLADMGFESGLATIALQRSNNDILQAVELLQTESDELTGASPWF-----PVTVDTTK---- 485
             ::..|..||:.:..|...|..::.::.:|:::|      |:....|:     |.|.:..:
Human   458 -NIRFLKGMGYSTHAAQQVLHAASGNLDEALKIL------LSNPQMWWLNDSNPETDNRQESPSQ 515

  Fly   486 --LAQLLQLGFNENDSRVALQNASNNMEEAIESLMCAIESEEELKAILKHVGRLAENGG------ 542
              :.:|:.:||:...:..||:....|::.|.::                    ||.|||
Human   516 ENIDRLVYMGFDALVAEAALRVFRGNVQLAAQT--------------------LAHNGGSLPPEL 560

  Fly   543 -----QNLDGPST--SNASGQTQVALPAPIIEAVINHARVEIETYKAYERFNSDLKLSDLEYLDL 600
                 .:|..|:|  |:::|.:..:...            ::|| :|......|:...:.:|||.
Human   561 PLSPEDSLSPPATSPSDSAGTSSASTDE------------DMET-EAVNEILEDIPEHEEDYLDS 612

  Fly   601 PLIQEEKILTEYFNMLQ 617
            .|..||.|:.||.:.::
Human   613 TLEDEEIIIAEYLSYVE 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15445	NP_001259756.1	UBA1_NUB1_like	354..391	CDD:270477	12/36 (33%)
		UBA_like_SF	429..463	CDD:304366	6/33 (18%)
		UBA_like_SF	484..519	CDD:304366	7/40 (18%)
NUB1	XP_016867793.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156762
Domainoid	1	1.000	138	1.000	Domainoid score	I4856
eggNOG	1	0.900	-	-		E1_KOG2561
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41108
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3603
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48673
OrthoDB	1	1.010	-	-		D1339766at2759
OrthoFinder	1	1.000	-	-		FOG0005370
OrthoInspector	1	1.000	-	-		otm40684
orthoMCL	1	0.900	-	-		OOG6_106196
Panther	1	1.100	-	-	O	PTHR12948
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5142
SonicParanoid	1	1.000	-	-		X4302
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.840