DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unc and T08D2.8

DIOPT Version :9

Sequence 1:	NP_001285512.1	Gene:	unc / 33093	FlyBaseID:	FBgn0003950	Length:	1386	Species:	Drosophila melanogaster
Sequence 2:	NP_001368073.1	Gene:	T08D2.8 / 353486	WormBaseID:	WBGene00011613	Length:	388	Species:	Caenorhabditis elegans

Alignment Length:	421	Identity:	81/421 - (19%)
Similarity:	130/421 - (30%)	Gaps:	170/421 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   599 PLPEKRESSVQTESTIPTASIATQTSRKSAHNESVITQTEQ-KQLKDAGNQASCEPPTFQKSYEQ 662
            ||....|:.:..::.......|...||..|.|:..|.:||: |||.:
Worm    89 PLSAYSEAGLSNKNPQARQQTALFLSRFFAKNDPKIVETEEVKQLAE------------------ 135

  Fly   663 WIHEMLHSSSGQVFLERVELSLNKALE------LQKVRLNELFQVKLRHQAEMLRLSKRQNSWRT 721
              |.:..|:.....:.:..|.:..|::      :.|..|.|::..||:  .|.|         ..
Worm   136 --HILKTSNDADKEVRKAALRIVAAVQKCLGEGVAKRLLAEVYHDKLK--TEKL---------PP 187

  Fly   722 LCKRVERDSQSSAEARDLVQQIFRLLEHYEAHHQQLAEKIQQTELAAEQAARIMPMWADGAAVGS 786
            |.:.:|::.:|||.     .::.||.:||:                                :||
Worm   188 LIEELEKEFESSAS-----PEMLRLAKHYK--------------------------------IGS 215

  Fly   787 ASVNWNTAMSTTLISSGICTPPPAQPAADGALNVGKTHVEQHTYPDLGYPYQLLALAPPGGVPVA 851
            :|                 |..|.:.||                   |.|.:|.:...|...|
Worm   216 SS-----------------TSAPPKTAA-------------------GAPKRLSSAVAPRRAP-- 242

  Fly   852 GTFVPVTHLPAHLLGASEHPV------------PLVPVARIYSDPMKT--------SRRLLSPSS 896
                |.:..|.....:.:.||            |:.|||.:...|...        .|..::|:.
Worm   243 ----PASAAPTRRAPSPKAPVVAPTRRAPSPKAPVAPVAPVKPKPFVARPAPNFGKPRAAVAPAR 303

  Fly   897 VPADNDSAHRAAGETNAFT--FQGGPVSGDLHPTENRNQAPATQGQQFPVPLPVPAPRGPSPSVQ 959
            .|   ....||...|...|  .:..|::    |...||.|||             |||.|   ::
Worm   304 AP---QITQRAPAATRPATSAIRVIPIA----PNVVRNGAPA-------------APRKP---IE 345

  Fly   960 SVLPSTASPALPPPDETVPQPGPSQSSIPLK 990
            ...|.|:|        .:..||..:|.|..|
Worm   346 IARPQTSS--------GIAAPGAPRSRIGTK 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unc	NP_001285512.1	LisH_2	225..252	CDD:292664
T08D2.8	NP_001368073.1	YCG1	101..>165	CDD:227543	15/83 (18%)
T08D2.8	NP_001368073.1	PHA03247	<219..361	CDD:223021	40/197 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960