DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15446 and ces-1

DIOPT Version :9

Sequence 1:	NP_608430.2	Gene:	CG15446 / 33088	FlyBaseID:	FBgn0031155	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_492338.1	Gene:	ces-1 / 185718	WormBaseID:	WBGene00000468	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	186	Identity:	33/186 - (17%)
Similarity:	71/186 - (38%)	Gaps:	29/186 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 SQSDSMVNTNQGFTTNRNFIPILSSFPNPYRNMDVTWTEQFNALSNQYYNHIMNSISSLSQIQPL 267
            |.:.|..:::...|::.|    |...|:..:|..|...:  |.|::|....:     .|...:.:
Worm    44 SSAASTSSSSSSSTSSEN----LKKSPSSVQNTSVFSID--NILNSQKVPKL-----ELENDEDV 97

  Fly   268 NSTPSANPPIFG--------ANPMVMGRHPPFSVFSCPLDYCKENFDSRRAMYKHQRETGHHNWP 324
            :|:||......|        .:...:.:..|.|...|..|.|.:::.:...:.:|::.....:.|
Worm    98 SSSPSPTCSTTGYTLDSLQNLDRRSLNKKGPSSHNRCVCDKCGKSYATTSNLSRHKQTHRALDSP 162

  Fly   325 H--NCSKCGQVFRTSGFMRM--------HSVNACARNLHKFKITKPNELQQLGKKP 370
            |  .|..|.:|:.:...:.|        |..|.|.:...:..:.:.:.....|.:|
Worm   163 HAKQCPHCDRVYVSMPALSMHILTHNASHECNVCGKRFSRLWLLQGHLRSHTGLRP 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15446	NP_608430.2	None
ces-1	NP_492338.1	C2H2 Zn finger	167..187	CDD:275368	4/19 (21%)
		C2H2 Zn finger	193..213	CDD:275368	2/19 (11%)
		zf-H2C2_2	206..229	CDD:290200	2/13 (15%)
		zf-C2H2	219..241	CDD:278523	33/186 (18%)
		C2H2 Zn finger	221..241	CDD:275368
		zf-H2C2_2	233..257	CDD:290200
		C2H2 Zn finger	249..268	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900