DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bves and POPDC3

DIOPT Version :9

Sequence 1:	NP_608426.1	Gene:	bves / 33083	FlyBaseID:	FBgn0031150	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_071756.2	Gene:	POPDC3 / 64208	HGNCID:	17649	Length:	291	Species:	Homo sapiens

Alignment Length:	215	Identity:	62/215 - (28%)
Similarity:	116/215 - (53%)	Gaps:	3/215 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 FQLGWAFLFLAFLAPHGPYGALWMRAMLLIGCLMMGMHGYLVAFAPDVILWSGMGLFVNFIYLVV 167
            :.|......:.|:...|.:|.|::.::|.:|.|...:..::...|.|:..|:.:...:.|:..|.
Human    30 YHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVH 94

  Fly   168 VLCRLRPVRFEQEIEAVYLALFQPLHVTRHQFKKVLNCMKVIRALKYQEVYAQEKVTKVDSLSLV 232
            :..::|.:.|.:|.:.:|.:|||||.::...|:.:....:|: .|:.:..||.:..|.:|.|||:
Human    95 IAYQVRSITFAREFQVLYSSLFQPLGISLPVFRTIALSSEVV-TLEKEHCYAMQGKTSIDKLSLL 158

  Fly   233 LSGKLVVSQHQRALHIVFPHQFLDSPEWFGV--STDDYFQVSIMAMEESRVLIWHRDKLKLSIMA 295
            :||::.|:.....||.:||.||||||||..:  :.:..|||::.|..:.|.:.|.|.||.|....
Human   159 VSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLFAQ 223

  Fly   296 EPFLQTVFDHILGRDVVKKL 315
            ..::..:|..::|.|:..||
Human   224 HRYISRLFSVLIGSDIADKL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bves	NP_608426.1	Popeye	98..320	CDD:282660	62/215 (29%)
POPDC3	NP_071756.2	Popeye	25..249	CDD:398483	62/215 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160531
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1369469at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42276
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5603
SonicParanoid	1	1.000	-	-		X2944
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880