DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stt3A and stt3b

DIOPT Version :9

Sequence 1:	NP_001259751.2	Gene:	Stt3A / 33082	FlyBaseID:	FBgn0031149	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	XP_031759383.1	Gene:	stt3b / 100495934	XenbaseID:	XB-GENE-969894	Length:	821	Species:	Xenopus tropicalis

Alignment Length:	729	Identity:	432/729 - (59%)
Similarity:	541/729 - (74%)	Gaps:	31/729 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GGVARGLLTWDKQEHLVKLAILILAAVLSFATRLFSVLRFESVIHEFDPYFNYRTTRFLAEQGFY 70
            ||::.||......:.|:...||.||.:..|::|||:|:||||:||||||:||||:|..||..|||
Frog    53 GGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFY 117

  Fly    71 KFHNWFDDRAWYPLGRIIGGTIYPGLMLTSAALYRLMWLLNVTIDIRNVCVFLAPFFSSLTTLVT 135
            :|.||||:|||||||||:|||:|||||:|:..::.::.:||:|:.||:|||||||.||.||::.|
Frog   118 EFLNWFDERAWYPLGRIVGGTVYPGLMVTAGLIHWILNMLNITVHIRDVCVFLAPVFSGLTSIST 182

  Fly   136 YALTKEIHSTGAGLVAAALISIVPGYISRSVAGSYDNEGIAIFCMLFTYYLWIKAVKTGTIFWSA 200
            :.||:|:.:.||||:||..|:|||||||||||||:||||||||.:.||||||:|:||||::||:.
Frog   183 FLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTI 247

  Fly   201 MSALAYFYMVSSWGGYVFLINLIPLHVLALMITGRFSHRIYIAYSTLYCVGTILSMQISFVGFQP 265
            ...|:||||||:||||||:||||||||..|::..|:|.|:||||||.|.||.||||||.||||||
Frog   248 CCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQP 312

  Fly   266 IQSSEHMLALGTFGLCQIHAFVDYLRSRIPKDHFDLLFKTLVSSVLTVVFVVGTLLTLTGKVSPW 330
            |::||||.|.|.|.|.|.:||:.|||.::.|..|..||...||....|||:....||.||.::||
Frog   313 IRTSEHMAAAGVFALLQAYAFLQYLRDKLSKQDFQTLFFLGVSLAAGVVFLTVIYLTYTGYIAPW 377

  Fly   331 TGRFYSLLDPSYAKNHIPIIASVSEHQPTSWSSFYFDLQILVFLFPAGLYFCFSKLTDSNIFIIL 395
            :||||||.|..|||.||||||||||||||:|.||:|||.|||..|||||:||...:.|..:|:.|
Frog   378 SGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVAL 442

  Fly   396 YGVTSIYFAGVMVRLMLVLAPVMCVLSGIAISHLLAKYI------------KSVDAGSSS----- 443
            |.::::|||||||||||.|.||:|:||.||.|::...|:            .|.|...:|
Frog   443 YAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGDDMKRENPPVEDSSDEERNSGTLYD 507

  Fly   444 KQGVESKR--QHKKLEQQTG-GVKSEVAIGFVGVITLMLIVYTLHCTWVTSEAYSSPSIVLSARS 505
            |.|...|.  :.:|.|:..| .:||.|.:    ::.::|:::.:|||||||.||||||:||::.:
Frog   508 KAGKVRKHVSEQEKAEEGLGPNIKSIVTM----LMLMLLMMFAVHCTWVTSNAYSSPSVVLASYN 568

  Fly   506 HDGGRIIFDDFREAYYWLQMNTPEDARIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAM 570
            |||.|.|.||||||||||:.||.|.||:||||||||||..|||||.|||||||||:||:.||:||
Frog   569 HDGTRNILDDFREAYYWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAM 633

  Fly   571 ASSEEKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAH---IREKDYYAAN 632
            :|:|..|||||:.|||||||:||||:.|||.||||||||||||.    .|.|   |||.||:...
Frog   634 SSNETAAYEIMKSLDVDYVLIIFGGVIGYSGDDINKFLWMVRIA----EGEHPKDIRESDYFTPQ 694

  Fly   633 GEFRVDKEGSPTLLNCLMYKMCYYRFGQMYTEGGKAQGYDRVRAAEIGNKDFELDVMEEAYTTEH 697
            |||||||.|||||||||||||.|||||:|..:.....|:||.|.|||||||.:...:|||:|:||
Frog   695 GEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEH 759

  Fly   698 WLVRIYKVKDLPNR 711
            |||||||||.|.||
Frog   760 WLVRIYKVKQLENR 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stt3A	NP_001259751.2	Stt3	19..712	CDD:224206	428/716 (60%)
Stt3A	NP_001259751.2	STT3	21..495	CDD:280649	276/493 (56%)
stt3b	XP_031759383.1	STT3	68..558	CDD:396873	276/493 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111618at33208
OrthoFinder	1	1.000	-	-		FOG0001875
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1235
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010