DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf150 and rnf150

DIOPT Version :9

Sequence 1:	XP_017168354.1	Gene:	Rnf150 / 330812	MGIID:	2443860	Length:	450	Species:	Mus musculus
Sequence 2:	NP_001135553.1	Gene:	rnf150 / 100216098	XenbaseID:	XB-GENE-5993052	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	451	Identity:	360/451 - (79%)
Similarity:	389/451 - (86%)	Gaps:	25/451 - (5%)

- Green bases have known domain annotations that are detailed below.

Mouse     1 MTMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYLEPEPGAAVAGSGGGAE 65
            |.||||||||||||||||||||||||||||||||||||||||||||||.:|.          ..:
Frog     1 MAMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYTDPL----------SHQ 55

Mouse    66 LHTEKSECGRYGEHSPKQDARGEVVMASSAQDRLACDPNTKFAAPAHGKHWIALIPKGNCTYRDK 130
            ..|||||||||||||.||||.|..||.||.||||||||.|||:.||:...|:|||||||||||||
Frog    56 WRTEKSECGRYGEHSLKQDAWGLAVMPSSPQDRLACDPATKFSVPANASRWVALIPKGNCTYRDK 120

Mouse   131 IRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITI 194
            |::|.|||||||:|:||| ||.||||||||.|:|||||||||||||:||.:||||||.||:||||
Frog   121 IKHAALQNASAVLIYNVGSSNANETITMPHPGIEDIVAIMIPEPKGREIATLLERNINVTIYITI 185

Mouse   195 GTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQYTIATGQDWQLYRRR 259
            ||||||||||||||||||||||||||||||||||||||||||||||||||             ||
Frog   186 GTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQ-------------RR 237

Mouse   260 LGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDH 324
            |||||||||||||||||:|||||||.:||||||||||||||||||||||||||||||||||||||
Frog   238 LGDAAKKAISKLQVRTIKKGDKETEPEFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDH 302

Mouse   325 RTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVG 389
            ||||||||||||||||||||||:||:|.|||||: ||||||||||||.|||||||.:||:|||||
Frog   303 RTCPMCKMNILKALGIPPNADCLDDIPPDFEGSV-GPPTNQITGASDVTVNESSVGIDPSVRTVG 366

Mouse   390 ALQVVQDPDPAPQEGEAIFTTNSGQEPALSSDSDISLIMALEVGLSDVELSTDQDCEEVKS 450
            .|||:||.:..||.||..:|.:|.||||:|||||||||||::||||||:|||||||:|.||
Frog   367 VLQVIQDAESLPQVGEVSYTASSEQEPAVSSDSDISLIMAVDVGLSDVDLSTDQDCDEAKS 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf150	XP_017168354.1	PA_GRAIL_like	45..192	CDD:239037	101/147 (69%)
Rnf150	XP_017168354.1	RING-H2_GRAIL	289..336	CDD:319582	46/46 (100%)
rnf150	NP_001135553.1	PA_GRAIL_like	45..183	CDD:239037	101/147 (69%)
		UPF0233	<197..>222	CDD:299753	24/24 (100%)
		zf-RING_2	266..309	CDD:290367	42/42 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I16654
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H33783
Inparanoid	1	1.050	723	1.000	Inparanoid score	I5031
OMA	1	1.010	-	-		QHG50669
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		oto196167
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3602
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110