DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbs and AT1G55880

DIOPT Version :9

Sequence 1:	NP_001285508.1	Gene:	Cbs / 33081	FlyBaseID:	FBgn0031148	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_175984.1	Gene:	AT1G55880 / 842038	AraportID:	AT1G55880	Length:	421	Species:	Arabidopsis thaliana

Alignment Length:	358	Identity:	106/358 - (29%)
Similarity:	165/358 - (46%)	Gaps:	56/358 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIE 113
            :::.||.|||:::|::..:.|  ||:..||||||||||||||:..:::|:|.|.|.|.||..:.|
plant    44 LVDAIGNTPLIRINSLSEATG--CEILGKCEFLNPGGSVKDRVAVKIIQEALESGKLFPGGIVTE 106

  Fly   114 PTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRT-PTEAAYDSPEGLIYVAQ 177
            .::|:|.|.||......|.||.:|:|:..:.||...:..|||.:.|. |....:  .:..:.:|:
plant   107 GSAGSTAISLATVAPAYGCKCHVVIPDDAAIEKSQIIEALGASVERVRPVSITH--KDHYVNIAR 169

  Fly   178 Q--------------------LQRETPNSIVL-------------------DQYRNAGNPLAHYD 203
            :                    :.:|..|...:                   ||:.|..|..|||:
plant   170 RRADEANELASKRRLGSETNGIHQEKTNGCTVEEVKEPSLFSDSVTGGFFADQFENLANYRAHYE 234

  Fly   204 GTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSIL-----------A 257
            ||..||..|....:|..|.:|||.||::|:.|.::::....:...:||.||.|           .
plant   235 GTGPEIWHQTQGNIDAFVAAAGTGGTLAGVSRFLQDKNERVKCFLIDPPGSGLYNKVTRGVMYTR 299

  Fly   258 RPAELNKTDVQFYEV-EGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGG 321
            ..||..:....|..: ||||.:.....|....:|...:..|.:...|||.|...:||..|.||..
plant   300 EEAEGRRLKNPFDTITEGIGINRLTKNFLMAKLDGGFRGTDKEAVEMSRFLLKNDGLFVGSSSAM 364

  Fly   322 AMHAALEHARKLKKGQRCVVILPDGIRNYMTKF 354
            ....|:..|:.|..|...|.||.|....:::||
plant   365 NCVGAVRVAQTLGPGHTIVTILCDSGMRHLSKF 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbs	NP_001285508.1	cysta_beta	45..505	CDD:273464	106/358 (30%)
		CBS_like	54..352	CDD:107204	103/349 (30%)
		CBS_pair_PALP_assoc	386..504	CDD:239981
AT1G55880	NP_175984.1	PLN02356	1..420	CDD:215204	106/358 (30%)
AT1G55880	NP_175984.1	PALP	46..388	CDD:278708	103/345 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016546at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100154
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X341
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.720