DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbs and CYSD2

DIOPT Version :9

Sequence 1:	NP_001285508.1	Gene:	Cbs / 33081	FlyBaseID:	FBgn0031148	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001031956.1	Gene:	CYSD2 / 832872	AraportID:	AT5G28020	Length:	323	Species:	Arabidopsis thaliana

Alignment Length:	326	Identity:	124/326 - (38%)
Similarity:	180/326 - (55%)	Gaps:	19/326 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 ITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPG- 108
            |..:|.|:||.||:|.|||:  .||....:.||.|.:.|..||||||.|.|::|||::||:.||
plant     7 IKNDITELIGNTPMVYLNNV--VDGCVARIAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGK 69

  Fly   109 YTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLI 173
            .|:||||:||||||||...|.:|||.|:|||..||.|:...||.|||::..:......   :|::
plant    70 STLIEPTAGNTGIGLACMGAARGYKVILVMPSTMSLERRIILRALGAELHLSDQRIGL---KGML 131

  Fly   174 YVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIK 238
            ...:.:..:||...:..|:.|..||..||..|..||......|||::|...||.||.:|:|:.:|
plant   132 EKTEAILSKTPGGYIPQQFENPANPEIHYRTTGPEIWRDSAGKVDILVAGVGTGGTATGVGKFLK 196

  Fly   239 EQVPSCQIVGVDPYGS-ILA--RPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDC 300
            ||....::..|:|..| :|:  :|..        :.::|||....|...|.|:||...::...:.
plant   197 EQNKDIKVCVVEPVESPVLSGGQPGP--------HLIQGIGSGIVPFNLDLTIVDEIIQVAGEEA 253

  Fly   301 FPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLKK-GQRCVVILPDGIRNYM-TKFVSDNWMEAR 363
            ...::.|..:||||.|.|||.|..|||:.|::.:. |:..||:.|.|...|: ||.......||.
plant   254 IETAKLLALKEGLLVGISSGAAAAAALKVAKRPENAGKLIVVVFPSGGERYLSTKLFDSIRYEAE 318

  Fly   364 N 364
            |
plant   319 N 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbs	NP_001285508.1	cysta_beta	45..505	CDD:273464	124/326 (38%)
		CBS_like	54..352	CDD:107204	115/303 (38%)
		CBS_pair_PALP_assoc	386..504	CDD:239981
CYSD2	NP_001031956.1	PLN00011	1..323	CDD:177651	124/326 (38%)
CYSD2	NP_001031956.1	PLN02565	3..323	CDD:166206	124/326 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	206	1.000	Domainoid score	I821
eggNOG	1	0.900	-	-		E1_COG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I1254
OMA	1	1.010	-	-		QHG54083
OrthoDB	1	1.010	-	-		D1016546at2759
OrthoFinder	1	1.000	-	-		FOG0000642
OrthoInspector	1	1.000	-	-		otm2614
orthoMCL	1	0.900	-	-		OOG6_100154
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X341
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780