Protein Alignment Cbs and T25D3.3

DIOPT Version :10

• Sequence 1: NP_608424.1
• Gene: Cbs / 33081
• FlyBaseID: FBgn0031148
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_493671.2
• Gene: T25D3.3 / 188894
• WormBaseID: WBGene00020797
• Length: 427
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 90/373 - (24%)
• Similarity: 147/373 - (39%)
• Gaps: 87/373 - (23%)

  Fly    52 VIGCTPLVKLN--NIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEP 114
            ::|.||:..::  .:|:     ..:..|.|..:..||:|.|..:.::..|..:|.:|.|..:.|.
 Worm    61 LMGSTPIHVIDPPGLPS-----VRLVFKNESASLTGSLKHRYSWSLMMWALLEGHVKNGTHVFEA 120

  Fly   115 TSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQL 179
            :||||...|...|.:.|.:...|:|:.:...||..:......::|.|..      :.|| :|:||
 Worm   121 SSGNTACSLGYMCRLLGLQFTAVVPDTIEQVKVRRIEEQEGFVVRVPIS------DRLI-IAEQL 178

  Fly   180 QRETPNSIVLDQYRNAGNPLA-HYDGTAA---------EILWQLDNKVDMIVV-SAGTAGTISGI 233
            .:.| ....::|::||.:... |..|:|:         |:..||::....|.| .|||.||:|.|
 Worm   179 AKST-GGFFMNQFKNAFHAEEFHESGSASSKPSANLMHELFHQLNSTPPSIFVHPAGTGGTLSSI 242

  Fly   234 GRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYE--------------------VEGIGYD 278
            ||..|:.....:||..|...||             :|:                    :.||||.
 Worm   243 GRYAKKYGLDTEIVLADTQYSI-------------YYDYVLNGTFSKNTGAHHWVAPGMAGIGYG 294

  Fly   279 -------FPPTVFDDTVVDVWTKIGD---SDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKL 333
                   ...|..|..|:|...||.|   :....::|.:.     :.||:|.|....|..|...|
 Worm   295 AMGPAQIAETTSLDPAVIDRVLKIPDLASTAAMKVARDVG-----INGGTSTGVNFLAALHIGAL 354

  Fly   334 KKGQR--------CVVILPDGIRNYMTKFVSDNWMEARNFKEPVNEHG 373
            .:.|.        ...||.|..:.|.|.:.:..|:     .|....||
 Worm   355 IRAQNPKNQEIFTIATILADSGKYYETTYFNRKWI-----SEKFKTHG 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cbs	NP_608424.1	cysta_beta	45..505	CDD:273464	90/373 (24%)
T25D3.3	NP_493671.2	CysK	61..379	CDD:439802	84/348 (24%)