Protein Alignment Cbs and cbs-2

DIOPT Version :10

• Sequence 1: NP_608424.1
• Gene: Cbs / 33081
• FlyBaseID: FBgn0031148
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_494215.2
• Gene: cbs-2 / 186197
• WormBaseID: WBGene00018783
• Length: 662
• Species: Caenorhabditis elegans
• Alignment Length: 376
• Identity: 195/376 - (51%)
• Similarity: 248/376 - (65%)
• Gaps: 28/376 - (7%)

  Fly     5 KPYERPADFIDPG----KPSKC--KWHLGTAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNN 63
            ||. :|.:..||.    .|:|.  :|      ||....|  ..|..:..::|:.||.||||||.:
 Worm   299 KPI-KPREIFDPKVLDYDPTKMVGEW------KSSSKFR--PERPLVLDSVLDAIGKTPLVKLQH 354

  Fly    64 IPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPG------YTIIEPTSGNTGIG 122
            :|.:.|:.|.:|.||||||.|||.||||..:||:.||:.|  |||      .|:|||||||||||
 Worm   355 VPKAHGVRCNVYVKCEFLNAGGSTKDRIAKKMVEIAEKTG--KPGALTPGATTLIEPTSGNTGIG 417

  Fly   123 LAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSI 187
            |::..||:||||:|.||||||.||.:.|..||:.|:|||.|||::||...|.||.:|:.|.|.::
 Worm   418 LSLVAAVRGYKCLITMPEKMSKEKSTTLSVLGSTIVRTPNEAAFNSPSSHIGVALRLKHEIPGAV 482

  Fly   188 VLDQYRNAGNPLAHYDGTAAEILWQL-DNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDP 251
            :||||.|.|||||||:.||.||||.: |.|:|::|:.|||.|||:||.|||.|:.|:..:|||||
 Worm   483 ILDQYCNPGNPLAHYEETAEEILWDMGDRKIDLVVLGAGTGGTITGISRKIHERRPNAIVVGVDP 547

  Fly   252 YGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCG 316
            .||||..|......|  |||||||||||.|...|:..||.|.|..|.:.|.|:|.:...||:|||
 Worm   548 NGSILTGPTTGPAPD--FYEVEGIGYDFIPGTLDEKSVDSWLKSDDKESFLMAREIIRTEGILCG 610

  Fly   317 GSSGGAMHAALEHARK--LKKGQRCVVILPDGIRNYMTKFVSDNWMEARNF 365
            ||||.|:|.|||..||  |.:....||:||||||||:|||:.|:||:||.|
 Worm   611 GSSGCAVHYALEQCRKLDLPEDANVVVLLPDGIRNYLTKFLDDDWMKARGF 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cbs	NP_608424.1	cysta_beta	45..505	CDD:273464	183/330 (55%)
cbs-2	NP_494215.2	CysK	7..289	CDD:439802
		cysta_beta	336..>662	CDD:273464	183/330 (55%)