Protein Alignment Cbs and cysl-1

DIOPT Version :10

• Sequence 1: NP_608424.1
• Gene: Cbs / 33081
• FlyBaseID: FBgn0031148
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001369978.1
• Gene: cysl-1 / 181209
• WormBaseID: WBGene00007653
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 319
• Identity: 130/319 - (40%)
• Similarity: 181/319 - (56%)
• Gaps: 18/319 - (5%)

  Fly    39 IAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQG 103
            :|.|..|..|...:||.||:|.:|.:  :.|:...:..|.|::||.||||||||..|:..||:.|
 Worm     1 MADRNSIGENAAALIGNTPMVYINKL--TKGLPGTVAVKIEYMNPAGSVKDRIGAAMLAAAEKDG 63

  Fly   104 LLKPGY-TIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRT-PTEAAY 166
            .:.||. |:||||||||||.||...|.|||:||:.||..||.|:.:.|:..|::::.| |.:..
 Worm    64 TVIPGVTTLIEPTSGNTGIALAFVAAAKGYRCIVTMPASMSGERRTLLKAYGSEVVLTDPAKGM- 127

  Fly   167 DSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTIS 231
               :|.|.:|.||:...|.||:|.|:.|..|||.||..|..||..|....||.:|...||.|||:
 Worm   128 ---KGAIDMANQLKENIPGSIILAQFDNPNNPLVHYQTTGPEIWRQTKGTVDAVVFGVGTGGTIT 189

  Fly   232 GIGRKIKEQVPSCQIVGVDPYGSIL--ARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTK 294
            |:||.::||.|..::..|:|..|.:  .|||..:|       ::|||..|.|.|.|..:.:...:
 Worm   190 GVGRYLQEQNPGVRVFAVEPEESAILSGRPAGPHK-------IQGIGAGFAPAVLDTKIYEDVIR 247

  Fly   295 IGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALE-HARKLKKGQRCVVILPDGIRNYMT 352
            |...:...|::||:.|||||.|.|||..:.|||: .||....|:..|..||.....|||
 Worm   248 IHSDEAIVMAQRLSYEEGLLGGISSGANVAAALQLAARPEMAGKLIVTCLPSCGERYMT 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cbs	NP_608424.1	cysta_beta	45..505	CDD:273464	128/313 (41%)
cysl-1	NP_001369978.1	CysK	7..305	CDD:439802	125/310 (40%)