DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1529 and ZIPIC

DIOPT Version :9

Sequence 1:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	87/347 - (25%)
Similarity:	142/347 - (40%)	Gaps:	45/347 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PHGFPTEICNLCHNAVVYFDELRQVARESSQKLIGWQPVDIAVD-----RVKEEPPDEGLKENHE 106
            |.|...|:....|..::          :.|::...:..||:.:|     .:.||...|..:..||
  Fly   136 PAGIVEEVAEEEHTFII----------KQSEEEDEFHSVDLELDIDNEIIINEEEAHEVEEVAHE 190

  Fly   107 ENE--HELEEE----HEKQADGQQVDLSKKQEDQKKILDDREDE--EYPDEYENSQQQLSQGTGS 163
            ..|  ||:|||    |:|| :.|:.|..|  ||.....|:..|.  ||.......|:|.::.:|
  Fly   191 IEEVAHEIEEEDLLPHDKQ-EAQEEDFFK--EDTMSDFDEHLDGAIEYIISDGEDQEQDNESSG- 251

  Fly   164 KRRAGLACDQCGKQVYKLPYLEAHIRSVH-QGYSKPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQ 227
            :....:.|..|.::.........|.:..| .||    :|..|.|:...|.....|::|..|
  Fly   252 EYTVNIQCPSCPEKFSSRRAYNVHTKREHFPGY----VCDQCGKTLQSYSGFIGHLQNHEP---- 308

  Fly   228 LQQELRDLICELCNRQYSTKNALGEHLKRHAQRKEHVCEHCGVAKVTRTELLTHLRTHNPTWERF 292
                ::...|.:|..::|.|..|..|:..|:....:.|:.|....|.:..|..|...|:...:|.
  Fly   309 ----VKQFACPVCPERFSRKFRLKHHMAWHSGETPYQCDVCSKRFVHKVALYKHKMIHDSETKRL 369

  Fly   293 KCEQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVRHERLHTESTGSGEAAEEWP 357
            :|:.|....|.|:.:.||:| .|.|.:.|.|..|.|:|....:...|.|.| ||.|:.....
  Fly   370 ECQVCGFKTRTKAHLERHMR-SHTGDKPFACPVCNKRFSQMYNMKAHLREH-ESPGTNRHRR--- 429

  Fly   358 FACIHCQKPCVSRQTLELHLRR 379
            |.|..|....::.|..:.|::|
  Fly   430 FHCSKCTHTFINEQNYDAHVQR 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	5/31 (16%)
		C2H2 Zn finger	171..192	CDD:275368	3/20 (15%)
		zf-C2H2_2	201..>257	CDD:289522	13/55 (24%)
		C2H2 Zn finger	201..222	CDD:275368	6/20 (30%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	265..285	CDD:275368	5/19 (26%)
		zf-C2H2_8	268..349	CDD:292531	25/80 (31%)
		C2H2 Zn finger	294..315	CDD:275368	7/20 (35%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	5/20 (25%)
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	6/19 (32%)
		zf-H2C2_2	327..351	CDD:290200	5/23 (22%)
		C2H2 Zn finger	342..391	CDD:275368	14/49 (29%)
		zf-H2C2_2	383..408	CDD:290200	10/25 (40%)
		C2H2 Zn finger	399..419	CDD:275368	6/19 (32%)
		C2H2 Zn finger	432..449	CDD:275368	3/16 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457189
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840