DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1529 and CG1024

DIOPT Version :9

Sequence 1:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001138014.2	Gene:	CG1024 / 40789	FlyBaseID:	FBgn0027514	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	86/433 - (19%)
Similarity:	147/433 - (33%)	Gaps:	147/433 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ILQK-LLDIDI-----------LKQPHGFPTEICNL-------CHNAVVYFDELRQVARESSQKL 79
            :||| |:|||:           |..|...|..|.|:       |.||  |.|.:|:..:|...|
  Fly   181 LLQKALMDIDLNTEMEKSPVTALAAPVNEPKPISNVSELNLDRCLNA--YEDIVRKEEKEVVPK- 242

  Fly    80 IGWQPVDIAVDRVKEEPPDEGLKENH-EENEHELEEEHEKQADGQQV------DLSKKQEDQKKI 137
                 .|..:|.:.:|..|:|..... |.||.:.:::...|...|:|      .|.|::..|.|
  Fly   243 -----YDDELDALCKEFFDDGPSAGKGEANEEQQQDDAHLQQGNQEVVIIEIDALGKEEVAQLK- 301

  Fly   138 LDDREDEEYPDEYENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYLEAHIRSVHQGYSK--PFL 200
                        .|.....:||.|  |||          ::...|..::.......|.:|  .:|
  Fly   302 ------------KEMKSDPISQPT--KRR----------RISTTPSRDSDTEMSTNGLTKLISYL 342

  Fly   201 CRSCDKSFTRYEQLRSHMRNAHPQLEQLQQEL------RDLICELCNRQYST--KNALGEHLKRH 257
            |..|.|.....:..|:|:...|.....::...      |..:|..|.....|  ::.|.:|..:|
  Fly   343 CPKCGKEIASMDGWRAHVFKKHDFEHIIENSFKILESGRKAMCLQCREVQPTTVRSQLQKHCFKH 407

  Fly   258 AQRKEHV-CEHCGVAKVTRTELLTHLRTHN-----------------PTW--------------- 289
            ...:.:: |..|...|.:.:::|.|:|.::                 |.|
  Fly   408 LPYRSYLKCTLCDRTKTSTSKILNHIRYNHQEELQRKNKTQLLIKPEPMWASPNKSGQAAMADDA 472

  Fly   290 -------ERFKCEQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVRHERLHTEST 347
                   |:..||.|.::||.|....||:            ..|.:                  :
  Fly   473 GSEDDQGEQAVCEHCDRVFRSKWRYERHI------------ASCRR------------------S 507

  Fly   348 GSGEAAEEWPFACIHCQKPCVSRQTLELHLRRHRARKTHRKRR 390
            |:|::.|....|.::        ...|.|:|.:...||.::.:
  Fly   508 GAGKSVEGTVEALLN--------HLREGHMRMNAIWKTMQREK 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	19/63 (30%)
		C2H2 Zn finger	171..192	CDD:275368	1/20 (5%)
		zf-C2H2_2	201..>257	CDD:289522	12/63 (19%)
		C2H2 Zn finger	201..222	CDD:275368	5/20 (25%)
		C2H2 Zn finger	237..257	CDD:275368	5/21 (24%)
		C2H2 Zn finger	265..285	CDD:275368	6/19 (32%)
		zf-C2H2_8	268..349	CDD:292531	17/119 (14%)
		C2H2 Zn finger	294..315	CDD:275368	8/20 (40%)
		C2H2 Zn finger	323..343	CDD:275368	1/19 (5%)
		C2H2 Zn finger	360..380	CDD:275368	3/19 (16%)
CG1024	NP_001138014.2	C2H2 Zn finger	30..51	CDD:275368
		C2H2 Zn finger	73..100	CDD:275368
		C2H2 Zn finger	106..123	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100