DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1529 and CTCF

DIOPT Version :10

Sequence 1:NP_001138223.2 Gene:CG1529 / 33077 FlyBaseID:FBgn0031144 Length:512 Species:Drosophila melanogaster
Sequence 2:NP_648109.1 Gene:CTCF / 38817 FlyBaseID:FBgn0035769 Length:818 Species:Drosophila melanogaster


Alignment Length:584 Identity:128/584 - (21%)
Similarity:200/584 - (34%) Gaps:185/584 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 PDPRLIAILQKLLDIDILKQ---------------PHGFPTEICNLCHNAVVYFDELRQVARESS 76
            |:|:.|::..........||               |.|.|.:      |.|:...|...:.|| .
  Fly   150 PEPKAISVRPARAAAAKAKQSAMPPPPALVVKVPAPRGRPRK------NPVIPKPEPMDLERE-L 207

  Fly    77 QKLIGWQPVDIAVDRVKEEPPDEGLKE-------NHEENEHELEEE---HEKQADGQQVD--LSK 129
            ::|:....:...|..:.:...||...|       .:|...:|.|:.   .::.||.:.||  ||.
  Fly   208 EELVDEPDISSMVTELSDYTVDEAAVEAATATLTPNEAEVYEFEDNATTEDENADKKDVDFVLSN 272

  Fly   130 KQEDQKKILDDREDEEYPDEYENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYLEAHIRSVHQG 194
            |:...|.              .:|..|.|..:|.|    .:|..|.....|...:..|.||  ..
  Fly   273 KEVKLKT--------------ASSTSQNSNASGHK----YSCPHCPYTASKKFLITRHSRS--HD 317

  Fly   195 YSKPFLCRSCDKSFTRYEQLRSHMRNAH----PQLEQLQQELRDLICELCNRQYSTKNALGEHLK 255
            ....|.|..|::||.....|::|: |.|    |..           |:||...::|...|..|.:
  Fly   318 VEPSFKCSICERSFRSNVGLQNHI-NTHMGNKPHK-----------CKLCESAFTTSGELVRHTR 370

  Fly   256 -RHAQRKEHVCEHCGVAKVTRTELLTHLRTHNPTWER-FKCEQCPQLFRHKSAISRHVRVVHEGQ 318
             :|.:.|.|.|..|..|.|..|:|..|:..|  |.|| ::|..|....:....:.||: |:|.|:
  Fly   371 YKHTKEKPHKCTECTYASVELTKLRRHMTCH--TGERPYQCPHCTYASQDMFKLKRHM-VIHTGE 432

  Fly   319 RRFQCGHCEKKFGTHASQVRHERLHTE-----------STGSGEAAE-----------EWPFACI 361
            :::||..|:.:|....|...|:.:|:.           .|..|..|:           :.|..|.
  Fly   433 KKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPTTCGRKADLRVHIKHMHTSDVPMTCR 497

  Fly   362 HCQKPCVSRQTLELHLRRHRARKTH-------------------------------------RKR 389
            .|.:....|...:||::.|...|.:                                     |:|
  Fly   498 RCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHLASHMLIHLDEKPFHCDQCPQAFRQR 562

  Fly   390 R--------EHSRESQEQEQE-----------------------HDRDQEQGAREAQQDQLRKGE 423
            :        .|:.|.|..|..                       ...|....|||.:: :|:.|.
  Fly   563 QLLRRHMNLVHNEEYQPPEPREKLHKCPSCPREFTHKGNLMRHMETHDDSANAREKRR-RLKLGR 626

  Fly   424 KLR-QRD-----LSRESHRNEVTMQTSQRPNECQQGQESYD---PEPDPLEASQCKLEQEDALD 478
            .:| |:|     |.::.:   |.|...|..||.....||||   .||:..||       |||.|
  Fly   627 NVRLQKDGTVITLIKDQY---VDMDRDQEENEEDDNPESYDLAEIEPENSEA-------EDADD 680

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1529NP_001138223.2 zf-AD 11..79 CDD:462262 13/66 (20%)
C2H2 Zn finger 171..192 CDD:275368 6/20 (30%)
C2H2 Zn finger 201..222 CDD:275368 7/20 (35%)
C2H2 Zn finger 237..257 CDD:275368 6/20 (30%)
C2H2 Zn finger 265..285 CDD:275368 7/19 (37%)
C2H2 Zn finger 294..315 CDD:275368 5/20 (25%)
C2H2 Zn finger 323..343 CDD:275368 5/19 (26%)
C2H2 Zn finger 360..380 CDD:275368 5/19 (26%)
tolA 391..>495 CDD:236545 31/120 (26%)
CTCFNP_648109.1 FAP 116..>202 CDD:429334 11/57 (19%)
C2H2 Zn finger 296..316 CDD:275368 6/21 (29%)
COG5048 321..>621 CDD:227381 65/315 (21%)
C2H2 Zn finger 324..344 CDD:275368 7/20 (35%)
C2H2 Zn finger 352..373 CDD:275368 6/20 (30%)
C2H2 Zn finger 381..401 CDD:275368 7/19 (37%)
zf-H2C2_2 394..415 CDD:463886 8/22 (36%)
C2H2 Zn finger 409..429 CDD:275368 5/20 (25%)
zf-H2C2_2 422..446 CDD:463886 9/24 (38%)
C2H2 Zn finger 437..457 CDD:275368 5/19 (26%)
C2H2 Zn finger 467..485 CDD:275368 3/17 (18%)
C2H2 Zn finger 496..516 CDD:275370 5/19 (26%)
C2H2 Zn finger 524..544 CDD:275368 0/19 (0%)
zf-H2C2_2 536..561 CDD:463886 0/24 (0%)
C2H2 Zn finger 552..573 CDD:275368 2/20 (10%)
zf-C2H2 587..609 CDD:395048 0/21 (0%)
C2H2 Zn finger 589..609 CDD:275368 0/19 (0%)

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