DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1529 and CG30431

DIOPT Version :9

Sequence 1:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	108/409 - (26%)
Similarity:	162/409 - (39%)	Gaps:	89/409 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TDLARLCRICLRHL---RDRDTHCPDPRLIAILQKLLDIDILKQPHGFPTEICNLCH-------- 59
            ||:  :|.:|||.|   ||....|....           .:|:..|.         |
  Fly    53 TDV--ICDLCLRRLHDARDFQRRCEHSE-----------QVLRMRHE---------HWKHTVAVG 95

  Fly    60 NAVVYFDELRQVARE-------SSQKLIGWQPVDIAVDRVKEEPPDEGLK-ENHEENEHELEEEH 116
            :|:...|.|..:.||       .|..|...:|| ..|..:.|....|.|. ::...:||::....
  Fly    96 DALALDDVLECLEREVGSLEGPMSVPLQASKPV-AHVAPLMETVDFESLDFQDSSHSEHDIPSYW 159

  Fly   117 EKQADGQQVDLSKKQEDQKKIL-------DDREDEEYPDEYENSQQQLSQGTGSKRRAGLACDQC 174
            |...|...::....|.:..::.       .:..:|..||..|..:.         |||....|..
  Fly   160 ESSVDSGSLNTPHHQPETAELFAVEPPTPPESSEEPAPDAAEKPKM---------RRARPRQDNV 215

  Fly   175 GKQVYKLPYLEAHIRSVHQGYSKPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDLICEL 239
            ..:..|... ..|.||:|.       |..|:|.|||..||:.||...|...|...|      ||.
  Fly   216 KPKERKASG-AVHPRSLHP-------CPECEKKFTRNFQLKLHMTAVHGMGEMRYQ------CEE 266

  Fly   240 CNRQYSTKNALGEHLKR-HAQRKEHVCEHCGVAKVTRTELLTHLRTHNPTWER----FKCEQCPQ 299
            |.:.::::::|..|:|. |:..:...|:||....:.||:||:|||||  |.|.    |:|::|.:
  Fly   267 CRKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTH--TGEAKPRIFECQRCSK 329

  Fly   300 LFRHKSAISRHVRVVHEG-QRRFQCGHCEKKFGTHASQVRHERLHTESTGSGEAAEEWPFACIHC 363
            .:..||.:..|:|..:.. :|.|:|..|.|.|.|......|..:||     ||.    ||||.:|
  Fly   330 SWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHT-----GEK----PFACEYC 385

  Fly   364 QKPCVSRQTLELHLRRHRA 382
            .|...|...|..|:.|..|
  Fly   386 DKCYQSVGNLNNHMVRLHA 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	17/85 (20%)
		C2H2 Zn finger	171..192	CDD:275368	5/20 (25%)
		zf-C2H2_2	201..>257	CDD:289522	19/56 (34%)
		C2H2 Zn finger	201..222	CDD:275368	10/20 (50%)
		C2H2 Zn finger	237..257	CDD:275368	6/20 (30%)
		C2H2 Zn finger	265..285	CDD:275368	10/19 (53%)
		zf-C2H2_8	268..349	CDD:292531	29/85 (34%)
		C2H2 Zn finger	294..315	CDD:275368	6/20 (30%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	6/19 (32%)
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071	10/41 (24%)
		C2H2 Zn finger	234..255	CDD:275368	10/20 (50%)
		C2H2 Zn finger	264..285	CDD:275368	6/20 (30%)
		C2H2 Zn finger	293..313	CDD:275368	10/19 (53%)
		zf-C2H2_8	305..373	CDD:292531	24/69 (35%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..389	CDD:290200	11/31 (35%)
		C2H2 Zn finger	382..403	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100