DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1529 and wor

DIOPT Version :9

Sequence 1:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	89/368 - (24%)
Similarity:	146/368 - (39%)	Gaps:	88/368 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 LRQVARESSQKLIGWQ---------PVDIAVDRVKEEPPDEGLKENHEENEHELEEEHEKQADGQ 123
            |:.|||    .|:..|         |:|:..|           :||.:.|:.:::..::.....|
  Fly   222 LQNVAR----ALLSMQHMAPQHAPPPIDMEED-----------QENQDINQLKIKSSNDLYYQCQ 271

  Fly   124 QVD--------LSKKQEDQKKILDDREDEEYPDEYENSQQQL--SQGTGSKRRAGLACDQ---CG 175
            |.:        |.|.|:..              .||:::.::  ||..||    |...||   |.
  Fly   272 QCNKCYATYAGLVKHQQTH--------------AYESTEYKIIRSQPGGS----GAIVDQTEFCT 318

  Fly   176 KQVYKLPYLEAHIRSVHQGYSKP-----FLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDL 235
            .|...| ...|::.|. |...||     :.|:.|.||::.|..|..|.:...|..|. .|..:..
  Fly   319 DQASAL-IQAANVASA-QSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEG-NQVKKVF 380

  Fly   236 ICELCNRQYSTKNALGEHLKRHAQRKEHVCEHCGVAKVTRTELLT-HLRTHNPTWER-FKCEQCP 298
            .|:.|::.|.:..||..|::.|....:  |..||.| .:|..||. |:|||  |.|: |.|:.|.
  Fly   381 SCKNCDKTYVSLGALKMHIRTHTLPCK--CPICGKA-FSRPWLLQGHIRTH--TGEKPFSCQHCN 440

  Fly   299 QLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVRH--ERLHTESTGSGEAAEEWPFACI 361
            :.|..:|.:..|:: .|...:::.|..|.|.|...:...:|  ....||.:| |.:.....|
  Fly   441 RAFADRSNLRAHMQ-THSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSG-GPSGSGGGF--- 500

  Fly   362 HCQKPCVSRQTLELHLR----RHRARKTHRKRREHSRESQEQE 400
                   .:|.|:.||:    .|...:.:......|...:|:|
  Fly   501 -------DQQQLQQHLQVYEEGHNPHQLYYAGSVGSSNGEEEE 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	4/10 (40%)
		C2H2 Zn finger	171..192	CDD:275368	7/23 (30%)
		zf-C2H2_2	201..>257	CDD:289522	16/55 (29%)
		C2H2 Zn finger	201..222	CDD:275368	7/20 (35%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	265..285	CDD:275368	9/20 (45%)
		zf-C2H2_8	268..349	CDD:292531	26/84 (31%)
		C2H2 Zn finger	294..315	CDD:275368	5/20 (25%)
		C2H2 Zn finger	323..343	CDD:275368	5/21 (24%)
		C2H2 Zn finger	360..380	CDD:275368	4/23 (17%)
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	5/19 (26%)
		C2H2 Zn finger	317..334	CDD:275368	5/18 (28%)
		zf-C2H2	345..367	CDD:278523	7/21 (33%)
		C2H2 Zn finger	347..367	CDD:275368	7/19 (37%)
		PHA00732	379..>417	CDD:177300	11/40 (28%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-C2H2_8	405..482	CDD:292531	25/82 (30%)
		zf-C2H2	406..428	CDD:278523	9/24 (38%)
		C2H2 Zn finger	408..428	CDD:275368	9/20 (45%)
		zf-H2C2_2	421..444	CDD:290200	10/24 (42%)
		zf-C2H2	434..456	CDD:278523	6/22 (27%)
		C2H2 Zn finger	436..456	CDD:275368	5/20 (25%)
		zf-H2C2_2	448..473	CDD:290200	6/25 (24%)
		C2H2 Zn finger	464..481	CDD:275368	4/16 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457172
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030