DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1529 and Opbp

DIOPT Version :9

Sequence 1:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	92/433 - (21%)
Similarity:	148/433 - (34%)	Gaps:	133/433 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DIDILKQPHGFPTEICNLCHNAVVYFDELRQVARESSQKLIG-----------WQ-----PVDIA 88
            |.:...:.|| |...|  |..|....|.:.:||.:...:.:|           |:     |.::.
  Fly    42 DTESYDRAHG-PQAGC--CTGASGELDFIEEVAEDCISEEVGEEDIVYADVPLWELVEEVPANVK 103

  Fly    89 VDRVKEEPPD---------EGLKENHEENEHELEEEHEKQADGQQVDLSKKQEDQKKILDDREDE 144
            .::.:.||.:         ..:.||..:.|..:....|.....|| |...|...::|:
  Fly   104 AEKDQNEPSNSDRYFCYDCHSIFENRNKAEEHICPRAESGGSSQQ-DGDAKAPVRRKL------- 160

  Fly   145 EYPDEYENSQQQLSQGTGSKRRAG-LACDQCGKQVYKLPYLEAHIR----------------SVH 192
                      ..:|..||.:..:. ::|..|........:|:.|:|                ..|
  Fly   161 ----------ASVSARTGPRDASSVISCGICNTVFSSEKFLKFHMRIHENRAPKSIQDALPIGAH 215

  Fly   193 QGYSK--PFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLK 255
            |.||:  .|.|..|:|||.      ..:...|.|:.  |||..:::|.:|||::..:.....|.|
  Fly   216 QQYSELDQFYCEICNKSFD------ETLLTVHKQMH--QQESSEIMCSICNRKFENEVTYQMHQK 272

  Fly   256 RH------------AQR-----------------------------------KEHVCEHCGVAKV 273
            .|            |||                                   |.:.||.||....
  Fly   273 IHEKPRDSESSRKLAQRTSLDKEKPGFPCQYCERVFTRPFEKVKHERVHTGEKPYACEVCGKTFR 337

  Fly   274 TRTELLTHLRTHNPTWERFKCEQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVR 338
            ....|..|||||. ....:.|..|.:.|:.....|.|:| :|..:|:|.|..|.|.|.|......
  Fly   338 VSYSLTLHLRTHT-NIRPYVCTVCNKRFKSHQVYSHHLR-IHSSERQFSCDACPKTFRTSVQLYA 400

  Fly   339 HERLHTESTGSGEAAEEWPFACIHCQKPCVSRQTLELHLRRHR 381
            |:..||:           |:.|..|.:|..|...::.|::.|:
  Fly   401 HKNTHTK-----------PYRCAVCNRPFSSMYAVKNHMQTHK 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	10/38 (26%)
		C2H2 Zn finger	171..192	CDD:275368	5/36 (14%)
		zf-C2H2_2	201..>257	CDD:289522	16/55 (29%)
		C2H2 Zn finger	201..222	CDD:275368	5/20 (25%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	265..285	CDD:275368	8/19 (42%)
		zf-C2H2_8	268..349	CDD:292531	25/80 (31%)
		C2H2 Zn finger	294..315	CDD:275368	6/20 (30%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		C2H2 Zn finger	301..321	CDD:275368	0/19 (0%)
		zf-H2C2_2	316..336	CDD:290200	5/19 (26%)
		C2H2 Zn finger	329..349	CDD:275368	8/19 (42%)
		zf-H2C2_2	341..366	CDD:290200	9/25 (36%)
		C2H2 Zn finger	357..377	CDD:275368	6/20 (30%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		C2H2 Zn finger	411..431	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100