DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1529 and si:ch73-367f21.6

DIOPT Version :9

Sequence 1:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	XP_017207864.1	Gene:	si:ch73-367f21.6 / 100005030	ZFINID:	ZDB-GENE-120214-31	Length:	488	Species:	Danio rerio

Alignment Length:	339	Identity:	96/339 - (28%)
Similarity:	156/339 - (46%)	Gaps:	65/339 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 EYENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYLEAHIRSVHQGYSKPFLCRSCDKSFTRYEQ 213
            |.:|.::.:...||.|   ..||.:||:.......|::|:| :|.| .|||.|:.|.|||:..:.
Zfish   214 EKQNLERHMRIHTGEK---PFACPECGRSFRVKQDLKSHVR-IHTG-EKPFSCQQCGKSFSENKT 273

  Fly   214 LRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLKRHAQRKEHVCEHCGVAKVTRTEL 278
            |.||||        :....:..:|..|.|::..|..|..|::.|...|.:.|..||.:...:..|
Zfish   274 LESHMR--------IHTGEKPFVCSHCGRRFRGKQNLESHMRLHTGEKRYTCPQCGKSYNEQKSL 330

  Fly   279 LTHLRTHNPTWER-FKCEQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVRHERL 342
            ..|:|||  |.|: |.|::|.:.||.:|.:..|:: :|.|::.|.|..|.|.|.......||:::
Zfish   331 QIHIRTH--TGEKPFACDECGKSFRQQSTLRGHIK-IHTGEKPFTCPQCGKSFIEKTKLERHKKI 392

  Fly   343 HTESTGSGEAAEEWPFACIHCQKPCVSRQTLELHLRRHRARKTHRKRREHSRESQEQEQEHDRDQ 407
            |     |||.    ||.|.||:|....:|:|::|:|.|...|.:                  ..|
Zfish   393 H-----SGEK----PFDCHHCKKSFTMKQSLDIHMRIHTGEKLY------------------TCQ 430

  Fly   408 EQGAREAQQDQLRKGEKLRQRDLSRESHRNEVTMQTSQRPNECQQGQESYDPEPDPLEASQCKLE 472
            :.|.....:.:|             |.|   :|:.|.::|..|||   |:..:|..:  |..|:.
Zfish   431 QCGKSFTVKHKL-------------ERH---MTVHTGEKPYTCQQ---SFREKPGLV--SHIKVH 474

  Fly   473 QEDALDPEWQHKIE 486
            .|:..:||.:..:|
Zfish   475 TEEKPEPEVEVVLE 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071
		C2H2 Zn finger	171..192	CDD:275368	6/20 (30%)
		zf-C2H2_2	201..>257	CDD:289522	16/55 (29%)
		C2H2 Zn finger	201..222	CDD:275368	10/20 (50%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	265..285	CDD:275368	6/19 (32%)
		zf-C2H2_8	268..349	CDD:292531	26/81 (32%)
		C2H2 Zn finger	294..315	CDD:275368	6/20 (30%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	8/19 (42%)
si:ch73-367f21.6	XP_017207864.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910