DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1532 and MCEE

DIOPT Version :9

Sequence 1:	NP_001285505.1	Gene:	CG1532 / 33076	FlyBaseID:	FBgn0031143	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_115990.3	Gene:	MCEE / 84693	HGNCID:	16732	Length:	176	Species:	Homo sapiens

Alignment Length:	161	Identity:	37/161 - (22%)
Similarity:	60/161 - (37%)	Gaps:	50/161 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 RAAEHSYPVTQVSGKAGSL-------LTSPDGYK---FYVIDQASASSDPVQSVELNVS----NL 151
            ||:..|.|:.||:|...:|       :..||..|   ||.....:..|:.|...|..||    ||
Human    27 RASSTSQPLDQVTGSVWNLGRLNHVAIAVPDLEKAAAFYKNILGAQVSEAVPLPEHGVSVVFVNL 91

  Fly   152 QNSR-KYWHDLLQ----LKVLEENEASVRLSYGEQQASLEITQISEPINRAK------------- 198
            .|:: :..|.|.:    ...|::|:|.     |.....:|:..|:..:...|
Human    92 GNTKMELLHPLGRDSPIAGFLQKNKAG-----GMHHICIEVDNINAAVMDLKKKKIRSLSEEVKI 151

  Fly   199 -AYGR-IAFAIPAAQQPPLQEAVKAAGGAIL 227
             |:|: :.|..|           |..||.::
Human   152 GAHGKPVIFLHP-----------KDCGGVLV 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1532	NP_001285505.1	Glo_EDI_BRP_like_21	6..133	CDD:176706	13/41 (32%)
CG1532	NP_001285505.1	Glo_EDI_BRP_like	143..256	CDD:211348	22/109 (20%)
MCEE	NP_115990.3	metmalonyl_epim	47..175	CDD:213772	29/141 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0346
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810