DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1532 and glod-4

DIOPT Version :9

Sequence 1:	NP_001285505.1	Gene:	CG1532 / 33076	FlyBaseID:	FBgn0031143	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_497827.1	Gene:	glod-4 / 175530	WormBaseID:	WBGene00006448	Length:	281	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	129/282 - (45%)
Similarity:	186/282 - (65%)	Gaps:	9/282 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISGRALHYVFKIGDRAKNAFFFRQILGMTVLRHEEFKEGCDAACNGPYDNRWSKTMVGYGPESSH 68
            ::.||||||||:.:|||...||..:|.|.|||||||::||:|.|||||:.||||||:|||.|..|
Worm     1 MTARALHYVFKVANRAKTIDFFTNVLNMKVLRHEEFEKGCEATCNGPYNGRWSKTMIGYGSEDEH 65

  Fly    69 FVIELTYNYGVSSYEMGNDFGGVTIHSKDILSRAAEHSYPVTQVSGKAGSLLTSPDGYKFYV--I 131
            ||:|:||||.:..||:|||:..:.|.|..:..:..:.::   :.||.....:..|||::|.:  .
Worm    66 FVLEITYNYPIHKYELGNDYRAIVIDSDQLFEKVEKINH---RKSGCGRLAVKDPDGHEFKIGKA 127

  Fly   132 DQASASSDPVQSVELNVSNLQNSRKYWHDLLQLKVLEENEASVRLSYGEQQASLEITQISEPINR 196
            ||    |..|..|::||.:|:.|:|||::.|.:.::||..:.:|:|||:.|..|||.:..:.|:|
Worm   128 DQ----SPKVLRVQVNVGDLEKSKKYWNETLGMPIVEEKSSRIRMSYGDGQCELEIVKSQDKIDR 188

  Fly   197 AKAYGRIAFAIPAAQQPPLQEAVKAAGGAILTPLITLDTPGKATVTVVILGDPDGHEICFVDEEG 261
            ...:|||||:.|..:...||:.:|:|.|.|:..|.||:|||||.|.||||.|||.||||||.:||
Worm   189 KTGFGRIAFSYPEDKLESLQDKIKSANGTIINELTTLETPGKADVQVVILADPDEHEICFVGDEG 253

  Fly   262 FGQLSQVESDGDKRLDRNIEKD 283
            |..||:::...:..|...|:||
Worm   254 FRALSKIDDKAESELKEQIKKD 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1532	NP_001285505.1	Glo_EDI_BRP_like_21	6..133	CDD:176706	61/128 (48%)
CG1532	NP_001285505.1	Glo_EDI_BRP_like	143..256	CDD:211348	52/112 (46%)
glod-4	NP_497827.1	Glo_EDI_BRP_like_21	3..127	CDD:176706	61/126 (48%)
glod-4	NP_497827.1	Glyoxalase	132..248	CDD:279274	53/115 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158780
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0346
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9376
Inparanoid	1	1.050	269	1.000	Inparanoid score	I1849
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59570
OrthoDB	1	1.010	-	-		D390402at33208
OrthoFinder	1	1.000	-	-		FOG0005578
OrthoInspector	1	1.000	-	-		oto18475
orthoMCL	1	0.900	-	-		OOG6_105403
Panther	1	1.100	-	-	LDO	PTHR46466
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2544
SonicParanoid	1	1.000	-	-		X3441
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800