Protein Alignment CG1304 and PRSS1

DIOPT Version :10

• Sequence 1: NP_608418.1
• Gene: CG1304 / 33074
• FlyBaseID: FBgn0031141
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 77/255 - (30%)
• Similarity: 122/255 - (47%)
• Gaps: 32/255 - (12%)

  Fly    14 LLLLAVPVHSAPGSLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILSRNYVLTAAHCVTNQD 78
            :|.......:||...:.::|||.:..:|..|:|||| |:|.|.||||:::..:|::|.||..:
Human     6 ILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKS-- 67

  Fly    79 SNGNSVPIAAERFTIRAG--------SNDRFSGGVLVQVAEVIVHEEYG--NFLNDVALLRLESP 133
                       |..:|.|        .|::|     :..|::|.|.:|.  ...||:.|::|.|.
Human    68 -----------RIQVRLGEHNIEVLEGNEQF-----INAAKIIRHPQYDRKTLNNDIMLIKLSSR 116

  Fly   134 LILSASIQPIDLPTADTPADVDVIISGWGRIKHQG-DLPRYLQYNTLKSISLERCDELIGWGVQS 197
            .:::|.:..|.||||........:|||||.....| |.|..||......:|..:|:......:.|
Human   117 AVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITS 181

  Fly   198 ELCLIHEADNG--ACNGDSGGPAVYNNQVVGVAGFVWSACGTSYPDGYARVYYHNEWIKN 255
            .:..:...:.|  :|.||||||.|.|.|:.||..:.......:.|..|.:||.:.:||||
Human   182 NMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKN 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	74/237 (31%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	70/234 (30%)