Protein Alignment CG1304 and KLK12

DIOPT Version :10

• Sequence 1: NP_608418.1
• Gene: CG1304 / 33074
• FlyBaseID: FBgn0031141
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 76/255 - (29%)
• Similarity: 107/255 - (41%)
• Gaps: 43/255 - (16%)

  Fly    10 LGSFLLLLAVPVHSA--PGSLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILSRNYVLTAAH 72
            |..||||..:.:..|  |...||...|     :|..|.||.|....|..|||.::...:||||||
Human     3 LSIFLLLCVLGLSQAATPKIFNGTECG-----RNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62

  Fly    73 CVTNQDSNGNSVPIAAERFTIRAGSNDRFSGGVLVQV--AEVIVHEEYG----NFL-------ND 124
            |             :..|:.:|.|.:.      |.|:  .|.|.|..:.    .:|       :|
Human    63 C-------------SGSRYWVRLGEHS------LSQLDWTEQIRHSGFSVTHPGYLGASTSHEHD 108

  Fly   125 VALLRLESPLILSASIQPIDLPTADTPADVDVIISGWGRIKH-QGDLPRYLQYNTLKSISLERCD 188
            :.||||..|:.:::|:||:.||.....|..:..:||||...| :...|..||...|..:|...|.
Human   109 LRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173

  Fly   189 ELIGWGVQSEL-CLIHEADNGACNGDSGGPAVYNNQVVGVAGFVWSACGTSYPDGYARVY 247
            .:....:.|.: |........||.||||||.|....:.|:..  |.:.|....||...||
Human   174 GVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVS--WGSVGPCGQDGIPGVY 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	67/231 (29%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	69/236 (29%)