DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1304 and prss60.3

DIOPT Version :9

Sequence 1:	NP_608418.1	Gene:	CG1304 / 33074	FlyBaseID:	FBgn0031141	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	252	Identity:	79/252 - (31%)
Similarity:	121/252 - (48%)	Gaps:	33/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 APGSLNGRVVGGEDAVKNQFPHQVSLRNA--GSHSCGGSILSRNYVLTAAHCVTNQDSNGNSVPI 86
            ||  ||.|:|||.:|....:|.||||.:.  |.|.||||::|..:|||||||::.         :
Zfish    30 AP--LNTRIVGGVNASPGSWPWQVSLHSPKYGGHFCGGSLISSEWVLTAAHCLSG---------V 83

  Fly    87 AAERFTIRAGSNDRFSGGVLV-----QVAEVIVHEEYGNFL--NDVALLRLESPLILSASIQPID 144
            :.....:..|.  |...|:.:     .||:..||..|.:..  ||:|||||.|.:..:..|:|:.
Zfish    84 SETTLVVYLGR--RTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVC 146

  Fly   145 LPTADT--PADVDVIISGWGRIKHQGDLPR--YLQYNTLKSISLERCDELIGWG--VQSELCL-I 202
            |...::  .|.....|:|||.|:...:||.  .||...:..::.:||:.|:|.|  ..:.:|. :
Zfish   147 LAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNALLGSGTVTNNMICAGL 211

  Fly   203 HEADNGACNGDSGGPAVYNNQVV----GVAGFVWSACGTSYPDGYARVYYHNEWIKN 255
            .:.....|.||||||.|.....|    |:..:.:.....:.|..|.||..:..||.:
Zfish   212 TQGGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCADPNSPGVYTRVSQYQSWISS 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1304	NP_608418.1	Tryp_SPc	31..253	CDD:214473	73/241 (30%)
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	74/244 (30%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	74/244 (30%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930