Protein Alignment CG1304 and F12

DIOPT Version :10

• Sequence 1: NP_608418.1
• Gene: CG1304 / 33074
• FlyBaseID: FBgn0031141
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 87/294 - (29%)
• Similarity: 132/294 - (44%)
• Gaps: 69/294 - (23%)

  Fly    20 PVHSAPGSL------------NG----------------RVVGGEDAVKNQFPHQVSLRNAGSHS 56
            |....||:|            ||                |||||..|::...|:..:|  ...||
Human   333 PQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAAL--YWGHS 395

  Fly    57 -CGGSILSRNYVLTAAHCVTNQDSNGNSVPIAAERFTIRAGSNDRFSGGVLVQ---VAEVIVHEE 117
             |.||:::..:|||||||:.::.        |.|..|:..|...|.......|   |....:||.
Human   396 FCAGSLIAPCWVLTAAHCLQDRP--------APEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEA 452

  Fly   118 YG--NFLNDVALLRLE-----SPLILSASIQPIDLPT-ADTPADVDVI-ISGWGRIKHQ----GD 169
            :.  ::.:|:|||||:     |..:||..:||:.||: |..|::..:. ::|||   ||    .:
Human   453 FSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWG---HQFEGAEE 514

  Fly   170 LPRYLQYNTLKSISLERCD--ELIGWGV-QSELCL-IHEADNGACNGDSGGPAVYNNQV----VG 226
            ...:||...:..:|||||.  ::.|..: ...||. ..|....||.||||||.|..:|.    :.
Human   515 YASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLT 579

  Fly   227 VAGFV-W-SACG-TSYPDGYARVYYHNEWIKNNS 257
            :.|.: | |.|| .:.|..|..|.|:..||:.::
Human   580 LQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHT 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	80/251 (32%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359		6/25 (24%)
		Tryp_SPc	373..612	CDD:238113	80/251 (32%)