DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1304 and svh-1

DIOPT Version :9

Sequence 1:	NP_608418.1	Gene:	CG1304 / 33074	FlyBaseID:	FBgn0031141	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	260	Identity:	70/260 - (26%)
Similarity:	110/260 - (42%)	Gaps:	32/260 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLLLAVPVHSAPGSLNGRVVGGEDAVKNQFPHQVSLRNAG--SHSCGGSILSRNYVLTAAHCVTN 76
            |..:.|....|..|...|||||.:.|...||...:|||..  :|.||.|||.:.:::|||||...
Worm   695 LRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCFEE 759

  Fly    77 QDSNGNSVPIAAERFTIRAGSNDRFSGG-VLVQVAEVIVHEEYGN-FLNDVALLRLESPLI-LSA 138
            .:.      :::....:....|::..|. .:..:..:..:..|.: |.:|:|:|.:..|.| .:.
Worm   760 DER------VSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKDIFSHDIAILEIPYPGIEFNE 818

  Fly   139 SIQPIDLPTAD---TPADVDVIISGWGRIKHQGDLPRY---LQYNTLKSISLERC---DELIGWG 194
            ..|||.||:.|   ||.. ..::||||.:.     .||   ||...:..|:...|   .::....
Worm   819 YAQPICLPSKDFVYTPGR-QCVVSGWGSMG-----LRYAERLQAALIPIINRFDCVNSSQIYSSM 877

  Fly   195 VQSELCLIH-EADNGACNGDSGGPAVYNNQ-----VVGVAGFVWSACGTSYPDGYARVYYHNEWI 253
            .:|..|..: |....:|.||||||.....:     :.||..:.........|..|..|..:..||
Worm   878 SRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWI 942

Fly 254 253
Worm 943 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1304	NP_608418.1	Tryp_SPc	31..253	CDD:214473	64/241 (27%)
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	65/242 (27%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	65/242 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910