DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1304 and PRSS36

DIOPT Version :9

Sequence 1:	NP_608418.1	Gene:	CG1304 / 33074	FlyBaseID:	FBgn0031141	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	276	Identity:	79/276 - (28%)
Similarity:	112/276 - (40%)	Gaps:	39/276 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GSFLLLLAVPVHSAPGSL-------NGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILSRNYVL 68
            |:|......|....|..|       :.|:|||.:|....:|.||||.:.|.|.||||:::.::||
Human    19 GAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVL 83

  Fly    69 TAAHCVTNQDSNGNSVPIAAERFTIRAGSND-RFSGGVLVQVAEVIVHEEYG--NFLNDVALLRL 130
            :||||..   :||...|.|.....:...|.| ...|.....||.::|...|.  ....|:|||||
Human    84 SAAHCFM---TNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRL 145

  Fly   131 ESPLILSASIQPIDLPTAD------TPADVDVIISGWGRIKHQGDLPR--YLQYNTLKSISLERC 187
            .||..|..::.|:.||.|.      |..    ..:|||.::....||.  .||...|:.:....|
Human   146 ASPASLGPAVWPVCLPRASHRFVHGTAC----WATGWGDVQEADPLPLPWVLQEVELRLLGEATC 206

  Fly   188 DELIGWG---------VQSELCLIH-EADNGACNGDSGGPAVYNNQ----VVGVAGFVWSACGTS 238
            ..|....         :...||..: |.....|.||||||.|....    ..|:..|.:.....:
Human   207 QCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRN 271

  Fly   239 YPDGYARVYYHNEWIK 254
            .|..:..|..:..||:
Human   272 RPGVFTAVATYEAWIR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1304	NP_608418.1	Tryp_SPc	31..253	CDD:214473	72/246 (29%)
CG1304	NP_608418.1	Tryp_SPc	32..256	CDD:238113	73/248 (29%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	72/246 (29%)
		Tryp_SPc	47..289	CDD:238113	73/248 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010