Protein Alignment Ser6 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 80/257 - (31%)
• Similarity: 124/257 - (48%)
• Gaps: 41/257 - (15%)

  Fly    28 LNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHC--VSNEDVNHVITPIAAER 90
            :.||:|||..|..:::|.||||....:|.|||:::...::||||||  |:.|.|        .|.
Human   322 MTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKV--------LEG 378

  Fly    91 FTIRAGSNDRFSGGVLVQVAEVIVHEEYGNFLN--DVALLRLESPLILSASIQPIDLPTVDTPAD 153
            :.:.||:::.........:||:|::..|.:..:  |:||:||..||.|||.|.|..||.......
Human   379 WKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFS 443

  Fly   154 VDVV--ISGWGRIKHQGD----LPRYLQYNTLKSITRQQCEELIDFG--------FEGELCLLHQ 204
            ::..  |:|:|:.:...|    ..|.:|.|.   |..::|.:.:.:.        ..|:|    :
Human   444 LNETCWITGFGKTRETDDKTSPFLREVQVNL---IDFKKCNDYLVYDSYLTPRMMCAGDL----R 501

  Fly   205 VDNGACNGDSGGPAV--YNNQ--LVGVAGFVVDGCGS-TYPDGYARVFYFKDWI--KKHSDV 259
            ....:|.||||||.|  .||:  |.||..:.. |||. ..|..|.:|.....||  |..|:|
Human   502 GGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGT-GCGQRNKPGVYTKVTEVLPWIYSKMESEV 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	76/248 (31%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747
		Tryp_SPc	325..554	CDD:214473	74/244 (30%)