DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ser6 and Klk12

DIOPT Version :9

Sequence 1:NP_523426.1 Gene:Ser6 / 33073 FlyBaseID:FBgn0011834 Length:259 Species:Drosophila melanogaster
Sequence 2:NP_081373.1 Gene:Klk12 / 69511 MGIID:1916761 Length:247 Species:Mus musculus


Alignment Length:264 Identity:74/264 - (28%)
Similarity:115/264 - (43%) Gaps:42/264 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 VAILLCSFLLFLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTA 70
            :.:|||:      :.:..|..:   ::..|.:.|||..|.||.|.:.....|||.::.|.::|||
Mouse     5 ILLLLCA------VGLSQADRE---KIYNGVECVKNSQPWQVGLFHGKYLRCGGVLVDRKWVLTA 60

  Fly    71 AHCVSNEDVNHVITPIAAERFTIRAGSNDRFSGGVLVQVAEV---IVHEEY-GNFLN---DVALL 128
            |||              .:::.:|.|.:.........|:...   |.|..| |.:.|   |:.||
Mouse    61 AHC--------------RDKYVVRLGEHSLTKLDWTEQLRHTTFSITHPSYQGAYQNHEHDLRLL 111

  Fly   129 RLESPLILSASIQPIDLPTVDTPADVDVVISGWGRIKHQGD-LPRYLQYNTLKSITRQQCEELID 192
            ||..|:.|:.:::|:.||:..........:||||......| .|..||...|.:::.:.|..:  
Mouse   112 RLNRPIHLTRAVRPVALPSSCVTTGAMCHVSGWGTTNKPWDPFPDRLQCLNLSTVSNETCRAV-- 174

  Fly   193 FGFEGE-----LCLLHQVDNGACNGDSGGPAVYNNQLVGVAGF-VVDGCGST-YPDGYARVFYFK 250
              |.|.     ||...:....||.||||||.|....|.|:..: .|..||.. .|..|.:|..:.
Mouse   175 --FPGRVTENMLCAGGEAGKDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQKGIPGVYTKVCKYT 237

  Fly   251 DWIK 254
            |||:
Mouse   238 DWIR 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ser6NP_523426.1 Tryp_SPc 31..253 CDD:214473 68/236 (29%)
Tryp_SPc 32..256 CDD:238113 70/238 (29%)
Klk12NP_081373.1 Tryp_SPc 21..240 CDD:214473 68/236 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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