Protein Alignment Ser6 and PRSS8

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 91/284 - (32%)
• Similarity: 134/284 - (47%)
• Gaps: 47/284 - (16%)

  Fly     4 GKVAILLCSFLL-------FLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSI 61
            |.|||||...||       ....|...||   ..|:.||..||..|:|.|||:...|.|.||||:
Human    13 GAVAILLYLGLLRSGTGAEGAEAPCGVAP---QARITGGSSAVAGQWPWQVSITYEGVHVCGGSL 74

  Fly    62 LTRTYILTAAHCVSNEDVNHVITPIAAERFTIRAGSN--DRFSGGVLVQ-VAEVIVHEEY---GN 120
            ::..::|:||||..:|  :|      .|.:.::.|::  |.:|....|. :.::|.|..|   |:
Human    75 VSEQWVLSAAHCFPSE--HH------KEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGS 131

  Fly   121 FLNDVALLRLESPLILSASIQPIDLPTVDT--PADVDVVISGWGRIKHQGDL--PRYLQYNTLKS 181
             ..|:|||:|..|:..|..|:||.||..:.  |..:...::|||.:.....|  |:.||...:..
Human   132 -QGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPL 195

  Fly   182 ITRQQCEEL--ID-------FGFEGELCLLHQVDNG--ACNGDSGGPAVYNNQ----LVGVAGFV 231
            |:|:.|..|  ||       |..|..:|..: |:.|  ||.||||||.....:    |.|:..:
Human   196 ISRETCNCLYNIDAKPEEPHFVQEDMVCAGY-VEGGKDACQGDSGGPLSCPVEGLWYLTGIVSW- 258

  Fly   232 VDGCGS-TYPDGYARVFYFKDWIK 254
            .|.||: ..|..|.....:..||:
Human   259 GDACGARNRPGVYTLASSYASWIQ 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	79/249 (32%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	79/249 (32%)