Protein Alignment Ser6 and KLK7

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 76/264 - (28%)
• Similarity: 118/264 - (44%)
• Gaps: 29/264 - (10%)

  Fly     7 AILLCSFLLFLVLPVQSAPGKLNG-RVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTA 70
            ::||...:|.|.|.:::|..:..| :::.|....:...|.||:|.:.....|||.::...::|||
Human     4 SLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

  Fly    71 AHCVSNEDVNHVITPIAAERFTIRAGSN---DRFSGGVLVQVAEVIVHEEYG--NFLNDVALLRL 130
            |||..||             :|:..||:   ||  ....::.::...|..|.  ..:||:.|::|
Human    69 AHCKMNE-------------YTVHLGSDTLGDR--RAQRIKASKSFRHPGYSTQTHVNDLMLVKL 118

  Fly   131 ESPLILSASIQPIDLPTVDTPADVDVVISGWGRIKHQG-DLPRYLQYNTLKSITRQQCEELI-DF 193
            .|...||:.::.:.||:...|......:||||...... ..|..|....:|.|:.|.|.::. |.
Human   119 NSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183

  Fly   194 GFEGELCL-LHQVDNGACNGDSGGPAVYNNQLVGVAGFVVDGCGSTYPDG-YARVFYFKDWI--- 253
            .....||. :......|||||||||.|....|.|:..:....||.....| |.:|..|..||
Human   184 LENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248

  Fly   254 -KKH 256
             |||
Human   249 MKKH 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	67/236 (28%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	64/230 (28%)