Protein Alignment Ser6 and PRSS2

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 79/259 - (30%)
• Similarity: 131/259 - (50%)
• Gaps: 28/259 - (10%)

  Fly    14 LLFLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHCVSNED 78
            :|..|....:||...:.::|||....:|..|:|||| |:|.|.||||:::..::::|.||..:.
Human     6 ILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHCYKSA- 68

  Fly    79 VNHVITPIAAE--RFTIRAG--------SNDRFSGGVLVQVAEVIVHEEYGN--FLNDVALLRLE 131
            :|..::....|  |..:|.|        .|::|     :..|::|.|.:|.:  ..||:.|::|.
Human    69 INSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQF-----INAAKIIRHPKYNSRTLDNDILLIKLS 128

  Fly   132 SPLILSASIQPIDLPTVDTPADVDVVISGWGRIKHQG-DLPRYLQYNTLKSITRQQCEELIDFGF 195
            ||.::::.:..|.|||....|..:.:|||||.....| |.|..||......:::.:||.......
Human   129 SPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKI 193

  Fly   196 EGELCLLHQVDNG--ACNGDSGGPAVYNNQLVGVA--GFVVDGCG-STYPDGYARVFYFKDWIK 254
            ...:..:..::.|  :|.||||||.|.|.:|.|:.  |:   ||. ...|..|.:|:.:.||||
Human   194 TNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY---GCAQKNRPGVYTKVYNYVDWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	75/241 (31%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	75/241 (31%)