DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ser6 and KLK15

DIOPT Version :9

Sequence 1:NP_523426.1 Gene:Ser6 / 33073 FlyBaseID:FBgn0011834 Length:259 Species:Drosophila melanogaster
Sequence 2:NP_059979.2 Gene:KLK15 / 55554 HGNCID:20453 Length:256 Species:Homo sapiens


Alignment Length:277 Identity:77/277 - (27%)
Similarity:119/277 - (42%) Gaps:58/277 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 ILLCSFLLFLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAH 72
            :|..||||      .|...:...:::.|::...:..|.||:|...|..:||.|:::..::|:|||
Human     4 LLTLSFLL------ASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62

  Fly    73 CVSNEDVNHVITPIAAERF-TIRAGSND---RFSGGVLVQVAEVIVHEEY--GNFLNDVALLRLE 131
            |.|              || .:|.|.::   |.....|...:.||.|..|  .:..||:.||||.
Human    63 CQS--------------RFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLV 113

  Fly   132 SPLILSASIQPIDLPTVDTPADVDVVISGWGRIKH-----------QGDLPRYLQYNTLKSITRQ 185
            .|..|:..::|..|||.........|:||||.:.|           |..||..|....:..|:..
Human   114 QPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178

  Fly   186 QCEE---------LIDFGFEGELCLLHQVDNGA--CNGDSGGPAVYNNQLVGVAGFVVDGC-GST 238
            .|::         ::..|.||         .||  |.||||||.|....|.|:..:....| .:|
Human   179 SCDKSYPGRLTNTMVCAGAEG---------RGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTT 234

  Fly   239 YPDGYARVFYFKDWIKK 255
            .|..|.:|.::.:||::
Human   235 KPGVYTKVCHYLEWIRE 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ser6NP_523426.1 Tryp_SPc 31..253 CDD:214473 69/250 (28%)
Tryp_SPc 32..256 CDD:238113 71/253 (28%)
KLK15NP_059979.2 Tryp_SPc 25..249 CDD:214473 69/246 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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