DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser6 and prss60.2

DIOPT Version :9

Sequence 1:	NP_523426.1	Gene:	Ser6 / 33073	FlyBaseID:	FBgn0011834	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	269	Identity:	82/269 - (30%)
Similarity:	126/269 - (46%)	Gaps:	32/269 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLCSFLLFLVLPVQS---------APGKLNGRVVGGEDAVKNQFPHQVSLRNA--GSHSCGGSIL 62
            |.|:.|..|:....|         ||  ||.|:|||.:|.:..:|.||||::.  |.|.||||::
Zfish     4 LTCATLTLLICVKGSLSQLNVCGQAP--LNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFCGGSLI 66

  Fly    63 TRTYILTAAHCVSNEDVNHVITPIAAERFTIRAGSNDRFSGGVLVQVAEVIVHEEYGNFL--NDV 125
            :..::||||||:.....:.::..:...   .:.|.|...:..   .||::|||..|.:..  ||:
Zfish    67 SSEWVLTAAHCLPGVSESSLVVYLGRR---TQQGVNTHETSR---NVAKIIVHSSYNSNTNDNDI 125

  Fly   126 ALLRLESPLILSASIQPIDLPTVDT--PADVDVVISGWGRIKHQGDLPR--YLQYNTLKSITRQQ 186
            |||||.|.:..:..|:|:.|...::  .|.....|:|||.::...:||.  .||...:..:...:
Zfish   126 ALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSSWITGWGDVQAGVNLPAPGILQETMIPVVANDR 190

  Fly   187 CEELIDFG--FEGELCL-LHQVDNGACNGDSGGPAVYNNQLVGV-AGFVVDGCGSTYPDG---YA 244
            |...:..|  ....:|. |.:.....|.||||||.|.....|.: ||....|.|...|:.   |.
Zfish   191 CNAQLGSGTVTNNMICAGLAKGGKDTCQGDSGGPMVTRLCTVWIQAGITSWGYGCADPNSPGVYT 255

  Fly   245 RVFYFKDWI 253
            ||..::.||
Zfish   256 RVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	71/236 (30%)
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	72/237 (30%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	71/236 (30%)
		Tryp_SPc	34..267	CDD:238113	72/237 (30%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840