Protein Alignment Ser6 and PLG

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 79/260 - (30%)
• Similarity: 119/260 - (45%)
• Gaps: 53/260 - (20%)

  Fly    22 QSAPGKLNGRVVGGEDAVKNQFPHQVSLRNA-GSHSCGGSILTRTYILTAAHCV----------- 74
            |..|.|..||||||..|..:.:|.|||||.. |.|.|||::::..::||||||:
Human   571 QVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKV 635

  Fly    75 ---SNEDVNHVITPIAAERFTIRAGSNDRFSGGVLVQVAEVIVHEEYGNFLNDVALLRLESPLIL 136
               ::::||  :.|...|                 ::|:.:.:...    ..|:|||:|.||.::
Human   636 ILGAHQEVN--LEPHVQE-----------------IEVSRLFLEPT----RKDIALLKLSSPAVI 677

  Fly   137 SASIQPIDLPTVD-TPAD-VDVVISGWGRIKHQGDL-PRYLQYNTLKSITRQQCE--ELIDFGFE 196
            :..:.|..||:.: ..|| .:..|:|||  :.||.. ...|:...|..|..:.|.  |.::...:
Human   678 TDKVIPACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQ 740

  Fly   197 G-ELCLLHQV-DNGACNGDSGGPAVYNNQ----LVGVAGFVVDGCG-STYPDGYARVFYFKDWIK 254
            . |||..|.. ...:|.||||||.|...:    |.||..:.: ||. ...|..|.||..|..||:
Human   741 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIE 804

  Fly   255  254
            Human   805  804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	74/250 (30%)
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	73/248 (29%)