Protein Alignment Ser6 and KLK12

DIOPT Version :9

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 73/260 - (28%)
• Similarity: 109/260 - (41%)
• Gaps: 49/260 - (18%)

  Fly    10 LCSFLLFLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHCV 74
            |..|||..||.:..|   ...::..|.:..:|..|.||.|....|..|||.::...::||||||
Human     3 LSIFLLLCVLGLSQA---ATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC- 63

  Fly    75 SNEDVNHVITPIAAERFTIRAGSNDRFSGGVLVQV--AEVIVHEEYG----NFL-------NDVA 126
                        :..|:.:|.|.:.      |.|:  .|.|.|..:.    .:|       :|:.
Human    64 ------------SGSRYWVRLGEHS------LSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLR 110

  Fly   127 LLRLESPLILSASIQPIDLPTVDTPADVDVVISGWGRIKH-QGDLPRYLQYNTLKSITRQQCEEL 190
            ||||..|:.:::|:||:.||.....|..:..:||||...| :...|..||...|..::...|..:
Human   111 LLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGV 175

  Fly   191 IDFGFEGEL-----CLLHQVDNGACNGDSGGPAVYNNQLVGVAGF-VVDGCGSTYPDGYARVFYF 249
                :.|.:     |........||.||||||.|....|.|:..: .|..||.   ||...|:.:
Human   176 ----YPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQ---DGIPGVYTY 233

  Fly   250  249
            Human   234  233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	66/239 (28%)
		Tryp_SPc	32..256	CDD:238113	66/238 (28%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	66/239 (28%)
		Tryp_SPc	22..236	CDD:238113	66/238 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920