DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser6 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_523426.1	Gene:	Ser6 / 33073	FlyBaseID:	FBgn0011834	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	86/272 - (31%)
Similarity:	129/272 - (47%)	Gaps:	59/272 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LPVQSAPGKLNG-----------RVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAH 72
            |.:.|:..|.:|           :|.||:||.:.::|.|.||:....|.||.::::.::::||||
  Rat   163 LLIDSSSFKFSGCGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAH 227

  Fly    73 CVSNEDVNHVITPIAAERFTIRAGSND-RFSGGVLVQ-------VAEVIVHEEYG----NFLNDV 125
            |                 |...|...| :.|.|.|:.       |..:::||.|.    |  ||:
  Rat   228 C-----------------FVRSANPKDWKVSFGFLLSKPQAQRAVKSIVIHENYSYPAHN--NDI 273

  Fly   126 ALLRLESPLILSASIQPIDLP--TVDTPADVDVVISGWGRIKHQGDLPRYLQYNTLKSITRQQCE 188
            |::||.||::...:|:...||  |...|.:.|||::|||.:|..||.|..||...:|.|..:.|.
  Rat   274 AVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCN 338

  Fly   189 ELIDFG---FEGELC---LLHQVDNGACNGDSGGPAVYNNQ-----LVGVAGFVVDGCG-STYPD 241
            ....:|   ..|.||   |..:||  ||.||||||.|..:.     |.|:..: .|.|. ...|.
  Rat   339 SGKAYGGVITPGMLCAGFLEGRVD--ACQGDSGGPLVSEDSKGIWFLAGIVSW-GDECALPNKPG 400

  Fly   242 GYARVFYFKDWI 253
            .|.||.:::|||
  Rat   401 VYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	80/247 (32%)
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	82/248 (33%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	80/247 (32%)
		Tryp_SPc	187..415	CDD:238113	82/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920