Protein Alignment Ser6 and PRSS41

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 81/271 - (29%)
• Similarity: 128/271 - (47%)
• Gaps: 61/271 - (22%)

  Fly    27 KLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHC-----------VSNEDVN 80
            :::..|.||.::.:.::|.|.|||....|.||||:|:|.::|:||||           |...::.
Human    66 EIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELT 130

  Fly    81 HVITPIAAERFTIRAGSNDRFSGGVLVQVAEVIVH-EEYGNFLNDVALLRLESPLILSASIQPID 144
            ...||     :.:||.|: |:      :|.::||: :..|...||:|||||.|.:..:|.||||.
Human   131 SRPTP-----WNLRAYSS-RY------KVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPIC 183

  Fly   145 LPT-----VDTPADVDVVISGWGRIKHQGDLPRYLQYN------TLKSITRQQCEELID------ 192
            :.:     |..|   |..::|||.|...| .|....||      |:.:.||  |..|.:
Human   184 IESSTFNFVHRP---DCWVTGWGLISPSG-TPLPPPYNLREAQVTILNNTR--CNYLFEQPSSRS 242

  Fly   193 FGFEGELCLLHQVDNGA---CNGDSGGPAVYNNQ----LVGVAGFVVDGCGS-TYPDGYARVFYF 249
            ..::...|.  ..::|:   |.||||||.|.:..    .||:..:.:| ||. ..|..|..:..:
Human   243 MIWDSMFCA--GAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMD-CGQPNRPGVYTNISVY 304

  Fly   250 KDWIKK---HS 257
            ..||::   ||
Human   305 FHWIRRVMSHS 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	79/263 (30%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	79/260 (30%)