DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser6 and Prss53

DIOPT Version :9

Sequence 1:	NP_523426.1	Gene:	Ser6 / 33073	FlyBaseID:	FBgn0011834	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	269	Identity:	67/269 - (24%)
Similarity:	102/269 - (37%)	Gaps:	61/269 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QSAPG---KLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHCVSNEDVNHVI 83
            |..||   ...|..:.||      :|.|.|:|..|.|.|.||::..|::||||||...      :
Mouse    30 QRGPGPPEPQEGNTLPGE------WPWQASVRRQGVHICSGSLVADTWVLTAAHCFEK------M 82

  Fly    84 TPIAAERFTIRAGS---NDRFSGGVLVQVAEVIVHEEYGNFL--NDVALLRLESPLILSASIQPI 143
            .......:::..||   ..:..|...|.||.:.:.:.|.::.  :|:|||:|..|.:.:....|
Mouse    83 ATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHPTVQTTLCLP- 146

  Fly   144 DLPTVDTPADVDVVISGWGRIKHQGDLPRYLQYNTLKSITRQQCEELIDFGFEGELCL---LHQ- 204
             .||...|.......:||.  ::..|:.|.|:...|:.|:|..|.           ||   |||
Mouse   147 -QPTYHFPFGASCWATGWD--QNTSDVSRTLRNLRLRLISRPTCN-----------CLYNRLHQR 197

  Fly   205 -----------------VDNGACNGDSGGPAVYNNQ-----LVGVAGFVVDGCGSTYPDGYARVF 247
                             .:.|.|.||||||.:....     .||:..|.........|.....:.
Mouse   198 LLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSKCAQEDTPVLLTDMA 262

  Fly   248 YFKDWIKKH 256
            ....|::.|
Mouse   263 VHSSWLQAH 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	61/252 (24%)
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	62/254 (24%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		4/15 (27%)
		Tryp_SPc	45..271	CDD:238113	62/252 (25%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010