Protein Alignment Ser6 and Klk12

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_001100978.2
• Gene: Klk12 / 308564
• RGDID: 1308975
• Length: 247
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 75/264 - (28%)
• Similarity: 114/264 - (43%)
• Gaps: 42/264 - (15%)

  Fly     6 VAILLCSFLLFLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTA 70
            :.:|||      |:.:..|..:   ::..|.:.|||..|.||.|.:.....|||.::.|.::|||
  Rat     5 ILLLLC------VVGLSQADRE---KIYNGVECVKNSQPWQVGLFHGKYLRCGGVLVDRKWVLTA 60

  Fly    71 AHCVSNEDVNHVITPIAAERFTIRAGSNDRFSGGVLVQ-------VAEVIVHEEYGNFLNDVALL 128
            |||              :.::.:|.|.:......:..|       :.....|..|.|..:|:.||
  Rat    61 AHC--------------SGKYMVRLGEHSLSKLDLTEQLRLTTFSITHPSYHGAYQNHEHDLRLL 111

  Fly   129 RLESPLILSASIQPIDLPTVDTPADVDVVISGWGRIKHQGD-LPRYLQYNTLKSITRQQCEELID 192
            ||..|:.|:.:::|:.||:...|......|||||......| .|..||...|..::.:.|..:
  Rat   112 RLNRPISLTYAVRPVALPSSCAPTGAKCHISGWGTTNKPWDPFPDRLQCLDLSIVSNETCRAV-- 174

  Fly   193 FGFEGE-----LCLLHQVDNGACNGDSGGPAVYNNQLVGVAGF-VVDGCGST-YPDGYARVFYFK 250
              |.|.     ||...:....||.||||||.|....|.|:..: .|..||.. .|..|.:|..:.
  Rat   175 --FPGRVTENMLCAGGEAGKDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQKGIPGVYTKVCKYT 237

  Fly   251 DWIK 254
            |||:
  Rat   238 DWIR 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	70/238 (29%)
Klk12	NP_001100978.2	Tryp_SPc	21..240	CDD:214473	68/236 (29%)