DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ser6 and GZMA

DIOPT Version :9

Sequence 1:NP_523426.1 Gene:Ser6 / 33073 FlyBaseID:FBgn0011834 Length:259 Species:Drosophila melanogaster
Sequence 2:NP_006135.2 Gene:GZMA / 3001 HGNCID:4708 Length:262 Species:Homo sapiens


Alignment Length:248 Identity:54/248 - (21%)
Similarity:98/248 - (39%) Gaps:40/248 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 LFLVLPVQSAPGKLNGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHCVSNEDV 79
            |.:|:.:...|..:..:::||.:...:..|:.|.|.......|.|:::.:.::||||||..|   
Human    12 LSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN--- 73

  Fly    80 NHVITPIAAERFTIRAGSNDRFSGGVLVQVAEVIVHEEY-------GNFLNDVALLRLESPLILS 137
                     :|..:..|::.........|:  ::|.:|:       .....|:.||:|.....::
Human    74 ---------KRSQVILGAHSITREEPTKQI--MLVKKEFPYPCYDPATREGDLKLLQLMEKAKIN 127

  Fly   138 ASIQPIDLPTV--DTPADVDVVISGWGRIKHQGDLPRYLQYNTLKSITRQQCEELIDFGFE---- 196
            ..:..:.||..  |........::||||..:.......|:...:..|.|:.|.:...:.|.    
Human   128 KYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIG 192

  Fly   197 ------GELCLLHQVDNGACNGDSGGPAVYNNQLVGVAGFVVDG-CGSTYPDG 242
                  |.|    :....:||||||.|.:......||..|.::. ||.  |.|
Human   193 MNMVCAGSL----RGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGD--PRG 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ser6NP_523426.1 Tryp_SPc 31..253 CDD:214473 51/232 (22%)
Tryp_SPc 32..256 CDD:238113 51/231 (22%)
GZMANP_006135.2 Tryp_SPc 29..254 CDD:238113 51/231 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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