Protein Alignment Ser6 and KLK13

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 77/277 - (27%)
• Similarity: 121/277 - (43%)
• Gaps: 47/277 - (16%)

  Fly     6 VAILLCSFLLFLVLPVQSAPGKL------NGRVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTR 64
            :|:::.|..|.|...|.....|:      :|.:.||.....:..|.|.:|...|...|||.::..
Human     4 LALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHP 68

  Fly    65 TYILTAAHCVSNEDVNHVITPIAAERFTIRAGSNDRFSGGVLVQVAEVIVHEEYG------NFLN 123
            .::||||||: .|.:...:...|..|  :.||...|       :|...|.|.||.      |..:
Human    69 KWVLTAAHCL-KEGLKVYLGKHALGR--VEAGEQVR-------EVVHSIPHPEYRRSPTHLNHDH 123

  Fly   124 DVALLRLESPLILSASIQPIDLPTVD--TPADVDVVISGWG-RIKHQGDLPRYLQYNTLKSITRQ 185
            |:.||.|:||:.|:..||.:.|...:  ||. ....:|||| ....|.:.|:.||...::..:.:
Human   124 DIMLLELQSPVQLTGYIQTLPLSHNNRLTPG-TTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDE 187

  Fly   186 QCEELIDFGFEGELCLLHQVDN-----------GACNGDSGGPAVYNNQLVGVAGFVVDGCGS-T 238
            :|.::    :.|::     .||           .:|.||||||.|.|..|.|:..:....||. .
Human   188 ECRQV----YPGKI-----TDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPD 243

  Fly   239 YPDGYARVFYFKDWIKK 255
            .|..|.||..:..||::
Human   244 RPGVYTRVSRYVLWIRE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	70/245 (29%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	70/243 (29%)