Protein Alignment Ser6 and KLK5

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 69/293 - (23%)
• Similarity: 115/293 - (39%)
• Gaps: 62/293 - (21%)

  Fly     9 LLCSFLLFLVL----------------PVQSAPGKLN-----------------GRVVGGEDAVK 40
            :||:.:..|:|                |..:.|...|                 .|::.|.|...
Human    11 VLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDM 75

  Fly    41 NQFPHQVS-LRNAGSHSCGGSILTRTYILTAAHCVSNEDVNHVITPIAAERFTIRAG----SNDR 100
            :..|.|.: |.......||..::...::||||||             ..:.|.:|.|    |...
Human    76 HTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-------------RKKVFRVRLGHYSLSPVY 127

  Fly   101 FSGGVLVQVAEVIVHEEYGN--FLNDVALLRLESPLILSASIQPIDLPTVDTPADVDVVISGWGR 163
            .||..:.|..:.|.|..|.:  ..||:.|::|...:..:..::||::.:....|....::||||.
Human   128 ESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGT 192

  Fly   164 IKH-QGDLPRYLQYNTLKSITRQQCEEL----IDFGFEGELCLLHQVDNGACNGDSGGPAVYNNQ 223
            .|. |...|:.||...:..:::::||:.    ||   :...|...:....:|.||||||.|.|..
Human   193 TKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQID---DTMFCAGDKAGRDSCQGDSGGPVVCNGS 254

  Fly   224 LVGVAGFVVDGCG-STYPDGYARVFYFKDWIKK 255
            |.|:..:....|. ...|..|..:..|..||::
Human   255 LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	61/237 (26%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/30 (13%)
		Tryp_SPc	66..285	CDD:214473	60/234 (26%)