Protein Alignment Ser6 and F10

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 74/251 - (29%)
• Similarity: 113/251 - (45%)
• Gaps: 46/251 - (18%)

  Fly    31 RVVGGEDAVKNQFPHQVSLRNAGSHS-CGGSILTRTYILTAAHCVSNEDVNHVITPIAAERFTIR 94
            |:|||::....:.|.|..|.|..:.. |||:||:..||||||||:           ..|:||.:|
Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCL-----------YQAKRFKVR 287

  Fly    95 AG--SNDRFSGGVLVQVAEVIVHEEYGNFLN-----DVALLRLESPLILSASIQPIDLPTVDTPA 152
            .|  :.::..||..|...||::  ::..|..     |:|:|||::|:....::.|..||..|...
Human   288 VGDRNTEQEEGGEAVHEVEVVI--KHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAE 350

  Fly   153 DVDV-----VISGWGRIKHQGDLPRYLQYNTLKSITRQQCEELIDF---------GFEGELCLLH 203
            ...:     ::||:||...:|.....|:...:..:.|..|:....|         |::.:
Human   351 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTK----- 410

  Fly   204 QVDNGACNGDSGGPAVYN-NQLVGVAGFVV--DGCGSTYPDG-YARVFYFKDWIKK 255
            |.|  ||.||||||.|.. .....|.|.|.  :||......| |.:|..|..||.:
Human   411 QED--ACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDR 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	73/250 (29%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	73/248 (29%)
		O-glycosylated at one site	476..485